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Table 3 Results from univariate and multivariate logistic regression analysis to test the risk of PPCs with diaphragm echodensity

From: Increased diaphragm echodensity correlates with postoperative pulmonary complications in patients after major abdominal surgery: a prospective observational study

Variable

Unadjusted OR (95%CI)

Unadjusted

P value

Model 1*

Model 2*

Model 3*

regression coefficient

SE

Odds Ratio (95%CI)

P value

regression coefficient

SE

Odds Ratio(95%CI)

P value

regression coefficient

SE

Odds Ratio(95%CI)

P value

Diaphragm echodensity

 EDmean

1.032 (1.028–1.036)

< 0.001

0.026

0.002

1.026 (1.022–1.029)

< 0.001

0.026

0.002

1.027 (1.022–1.031)

< 0.001

-0.061

-0.119

1.023 (1.018–1.029)

< 0.001

 ED50

1.037 (1.033–1.041)

< 0.001

0.031

0.002

1.032 (1.027–1.036)

< 0.001

0.034

0.002

1.034 (1.030–1.039)

0.002

0.031

0.003

1.031 (1.026–1.037)

< 0.001

 ED85

1.018 (1.016–1.020)

< 0.001

0.014

0.001

1.014 (1.012–1.017)

< 0.001

0.013

0.001

1.013 (1.011–1.016)

< 0.001

0.011

0.002

1.011 (1.008–1.014)

< 0.001

Age**

1.034 (1.030–1.038)

< 0.001

0.023

0.002

1.023 (1.019–1.027)

< 0.001

0.012

0.002

1.012 (1.008–1.017)

< 0.001

0.043

0.003

1.044 (1.038–1.050)

< 0.001

Emergency surgery**

5.030 (4.508–5.613)

< 0.001

1.584

0.058

4.873 (4.343–5.467)

< 0.001

1.245

0.072

3.473 (3.016–3.998)

< 0.001

1.259

0.090

3.522 (2.952–4.202)

< 0.001

APHACHE II score**

1.060(1.053–1.067)

< 0.001

    

0.026

0.004

1.027 (1.018–1.035)

< 0.001

0.027

0.005

1.028 (1.018–1.038)

< 0.001

FiO2 **

1.301 (1.264–1.339)

< 0.001

        

0.370

0.023

1.447 (1.384–1.513)

< 0.001

WBC**

1.152 (1.139–1.165)

< 0.001

        

0.182

0.008

1.199 (1.182–1.217)

< 0.001

PCT**

1.229 (1.190–1.269)

< 0.001

        

-0.024

0.008

0.976 (0.961–0.991)

0.002

ASA class**

 Grade 2

1 (Ref)

     

1 (Ref)

1 (Ref)

1 (Ref)

 

1 (Ref)

1 (Ref)

1 (Ref)

 

 Grade 3

6.467 (5.794–7.218)

< 0.001

    

1.237

0.066

3.446 (3.025–3.925)

< 0.001

0.887

0.073

2.428 (2.104–2.802)

< 0.001

 Grade 4

1.712 (1.382–2.127)

< 0.001

    

-0.599

0.139

0.549 (0.419–0.721)

< 0.001

-2.130

0.205

0.119 (0.079–0.178)

< 0.001

  1. Abbreviations: PPCs, Postoperative Pulmonary Complications; non-PPCs, no Postoperative Pulmonary Complications; APACHE II, Acute Physiology and Chronic Health Evaluation; ASA class, American Society of Anesthesiologists class; WBC, white blood cell. CRP, C-reactive protein; PCT, Procalcitonin; ICU, intensive care units; CI, Confidence interval
  2. *Model 1 was adjusted for age, emergency surgery and diaphragm echodensity. Model 2 was adjusted for age, emergency surgery, APHACHE II score, ASA class and diaphragm echodensity. Model 3 was adjusted for age, emergency surgery, APHACHE II score, ASA class, FiO2, WBC, PCT and diaphragm echodensity. Only variables with p < 0.05 are reported in models above
  3. ** There is collinearity among ED50, ED85 and EDmean and cannot be included in the same model. In Model 1, 2, and 3, the results for these variables were generated by only entering the ED50 into the multivariable-adjusted model. Among them, FiO2, WBC and PCT were obtained at ICU admission