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Table 3 The association of baseline diabetes status, follow-up time with lung function parameters through the mixed model

From: Association of lung function and blood glucose level: a 10-year study in China

 

Model 1

Model 2

Model 3

 

Estimate (95% CI)

p

Estimate (95% CI)

p

Estimate (95% CI)

p

FVC

 Diabetic status

  Normal

Ref

 

Ref

 

Ref

 

  Prediabetes

-0.117(-0.153 ~ -0.081)

< 0.001

-0.122(-0.165 ~ -0.080)

< 0.001

-0.104(-0.147 ~ -0.06)

< 0.001

  Diabetes

-0.188(-0.232 ~ -0.143)

< 0.001

-0.186(-0.239 ~ -0.133)

< 0.001

-0.140(-0.216 ~ -0.063)

< 0.001

  Time

-0.011(-0.013 ~ -0.010)

< 0.001

-0.012(-0.014 ~ -0.010)

< 0.001

-0.013(-0.015 ~ -0.011)

< 0.001

FEV1

 Diabetic status

  Normal

Ref

 

Ref

 

Ref

 

  Prediabetes

-0.069(-0.099 ~ -0.040)

< 0.001

-0.071(-0.106 ~ -0.037)

< 0.001

-0.057(-0.092 ~ -0.021)

0.002

  Diabetes

-0.112(-0.149 ~ -0.076)

< 0.001

-0.103(-0.146 ~ -0.061)

< 0.001

-0.061(-0.122 ~ 0.001)

0.055

  Time

-0.006(-0.007 ~ -0.004)

< 0.001

-0.006(-0.007 ~ -0.004)

< 0.001

-0.007(-0.009 ~ -0.005)

< 0.001

FVC%

 Diabetic status

  Normal

Ref

 

Ref

 

Ref

 

  Prediabetes

-2.944(-3.873 ~ -2.015)

< 0.001

-3.104(-4.190 ~ -2.018)

< 0.001

-2.554(-3.677 ~ -1.431)

< 0.001

  Diabetes

-4.892(-6.046 ~ -3.739)

< 0.001

-4.924(-6.275 ~ -3.574)

< 0.001

-3.809(-5.771 ~ -1.847)

0.001

  Time

0.150(0.102 ~ 0.197)

< 0.001

0.120(0.064 ~ 0.176)

< 0.001

0.091(0.035 ~ 0.147)

0.002

FEV1%

 Diabetic status

  Normal

Ref

 

Ref

 

Ref

 

  Prediabetes

-1.994(-2.886 ~ -1.101)

< 0.001

-2.043(-3.100 ~ -0.986)

< 0.001

-1.742(-2.828 ~ -0.655)

0.002

  Diabetes

-3.122(-4.230 ~ -2.013)

< 0.001

-3.014(-4.327 ~ -1.701)

< 0.001

-2.48(-4.377 ~ -0.584)

0.010

  Time

0.617(0.559 ~ 0.675)

< 0.001

0.616(0.547 ~ 0.685)

< 0.001

0.623(0.561 ~ 0.685)

< 0.001

FEV1/FVC

 Diabetic status

  Normal

Ref

 

Ref

 

Ref

 

  Prediabetes

0.786(0.273 ~ 1.300)

0.003

0.809(0.204 ~ 1.415)

0.009

0.78(0.156 ~ 1.405)

0.014

  Diabetes

1.341(0.703 ~ 1.979)

< 0.001

1.455(0.704 ~ 2.207)

< 0.001

1.513(0.421 ~ 2.605)

0.007

  Time

0.088(0.056 ~ 0.119)

< 0.001

0.105(0.066 ~ 0.0143)

< 0.001

0.098(0.059 ~ 0.137)

< 0.001

  1. Model 1 adjusted for age (continuous), sex (categorical); Model 2 further adjusted for smoking status (categorical), physical activity frequency (categorical); Model 3 further adjusted for body mass index (continuous), high total cholesterol (categorical), low HDL (categorical), high LDL (categorical), HTN status (categorical), diabetes medication history (categorical). All models contained an interaction term of baseline diabetes status and follow-up time, but none shown statistical significance (p > 0.05)