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Table 2 Radiological response criteria (H HARADA et al.: J. Radiat. Res. (2010))

From: Osteosclerotic change as a therapeutic response to gefitinib in symptomatic non-small cell lung cancer bone metastasis

Response Type

Initial plain radiography pattern

Sclerotic

Mixed

Lytic

Undetectable

Complete response (CR)

Normalization

Normalization Complete filling in

Normalization Complete filling in

Complete Sclerosis

Partial response (PR)

Regression in size

Sclerotic rim Partial filling in Regression in size

Sclerotic rim Partial filling in Regression in size

Sclerotic rim Partial filling in

No change (NC)

No change

No change

No change

No change

Progressive disease (PD)

Increase in size

Increase in size

Increase in size

Appearance of lytic lesion