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Table 2 Association between overall survival and development of CPA (n = 6777)

From: Mortality and lung function decline in patients who develop chronic pulmonary aspergillosis after lung cancer surgery

Models

Overall survival for CPA (+) (vs. CPA (–))

HR

95% CI

P

Crude

1.69

1.23–2.32

0.001

Model 1

1.10

0.80–1.51

0.565

Model 2

0.92

0.66–1.25

0.560

Model 3

0.73

0.53–1.03

0.060

  1. Model 1 was adjusted for clinical baseline characteristics (age, sex, body mass index, smoking status, and comorbidities: history of pulmonary tuberculosis, chronic obstructive pulmonary disease/asthma, interstitial lung disease, diabetes mellitus, and previous history of malignancy). Model 1 was analyzed by excluding 2 patients with missing data for smoking status
  2. Model 2 was adjusted for variables with lung cancer-related factors (tumor histology, types of surgical resection, postoperative pulmonary complications within 30 days, and neoadjuvant and adjuvant treatment: none, chemotherapy only, radiotherapy only, and chemotherapy and radiotherapy both). Model 2 was analyzed by excluding 50 patients with missing data for adjuvant treatment
  3. Model 3 was adjusted for all the preceding variables. Model 3 was analyzed by excluding 52 patients with missing data for smoking status or adjuvant treatment
  4. CPA Chronic pulmonary aspergillosis, HR Hazard ratio, CI Confidence interval
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BMC Pulmonary Medicine

ISSN: 1471-2466

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