Table 3 Comparison of lung function according to CPA development (n = 1842)
Variables | Total (n = 1842) | CPA (–) (n = 1792) | CPA (+) (n = 50) | P |
|---|---|---|---|---|
Interval between baseline and last spirometry procedure, years | 3.7 (1.8–4.4) | 3.7 (1.8–4.4) | 2.7 (1.5–4.7) | 0.678 |
Baseline spirometry after surgerya | ||||
 FVC, L | 2.96 (2.45–3.57) | 2.97 (2.46–3.59) | 2.70 (2.17–3.11) | 0.003 |
 FVC, % predicted | 81 (68–91) | 81 (69–91) | 65 (54–76) | < 0.001 |
 FEV1, L | 2.09 (1.73–2.51) | 2.09 (1.73–2.51) | 1.96 (1.56–2.31) | 0.116 |
 FEV1, % predicted | 77 (64–88) | 77 (65–88) | 64 (57–73) | < 0.001 |
 FEV1/FVC | 73 (66–79) | 73 (65–88) | 79 (70–84) | < 0.001 |
Baseline spirometry pattern | < 0.001 | |||
 Normal | 777 (42.2) | 770 (43.0) | 7 (14.0) |  |
 Obstructive | 520 (28.2) | 508 (28.3) | 12 (24.0) |  |
 Restrictive | 545 (29.6) | 514 (28.7) | 31 (62.0) |  |
Last spirometry results | ||||
 FVC, L | 3.01 (2.39–3.38) | 3.04 (2.41–3.39) | 2.35 (1.76–2.67) | < 0.001 |
 FVC, % predicted | 80 (67–92) | 81 (67–93) | 58 (42–69) | < 0.001 |
 FEV1, L | 1.99 (1.62–2.44) | 1.99 (1.63–2.45) | 1.76 (1.43–2.10) | 0.001 |
 FEV1, % predicted | 76 (63–89) | 77 (63–89) | 60 (45–70) | < 0.001 |
 FEV1/FVC | 71 (64–78) | 71 (64–78) | 77 (69–86) | < 0.001 |
Last spirometry pattern | < 0.001 | |||
 Normal | 744 (40.4) | 739 (41.2) | 5 (10.0) |  |
 Obstructive | 571 (31.0) | 559 (31.2) | 12 (24.0) |  |
 Restrictive | 527 (28.6) | 494 (27.6) | 33 (66.0) |  |
Changes in lung function | ||||
 FVC decline, mL/year | -13.2 (-87.1 to 56.4) | -10.9 (-82.6 to 57.9) | -71.0 (-272.9 to -19.4) | < 0.001 |
 FVC decline ≤ -40 mL/year | 734 (39.8) | 698 (39.0) | 36 (72.0) | < 0.001 |
 FEV1 decline, mL/year | -20.4 (-73.3 to 28.5) | -20.0 (-72.6 to 28.6) | -52.9 (-192.2 to 3.9) | 0.010 |
 FEV1 decline ≤ -40 mL/year | 725 (39.4) | 698 (39.0) | 27 (54.0) | 0.032 |
Use of bronchodilator during the follow-up period | 426 (23.1) | 397 (22.2) | 29 (58.0) | < 0.001 |