MRI-assessed diaphragmatic function can predict frequent acute exacerbation of COPD: a prospective observational study based on telehealth-based monitoring system

Table 2 Analysis of diaphragm function parameters between COPD and control groups

Variables	COPD group (N = 59)	Healthy control (N = 16)	t	P value
Diaphragmatic dome factor
Diaphragmatic dome factor (Insp)	1.15 ± 0.09	1.27 ± 0.11	− 4.42	P < 0.001
Diaphragmatic dome factor (Exp)	1.24 ± 0.13	1.32 ± 0.07	− 2.38	0.020
Anterior–posterior diameter of chest(cm)
Anterior–posterior diameter Insp(cm)	18.78 ± 1.61	17.20 ± 1.98	3.33	0.001
Anterior–posterior diameter Exp(cm)	16.88 ± 1.64	14.31 ± 1.92	5.37	P < 0.001
Chest wall motion(cm)	1.91 ± 1.07	2.89 ± 1.38	− 3.07	0.003
Lung area (cm²)
Lung area Insp (cm²)	355.25 ± 43.62	305.59 ± 42.17	4.07	P < 0.001
Lung area Exp (cm²)	244.28 ± 52.94	172.28 ± 29.04	7.19	P < 0.001
Change of lung area (cm²)	110.98 ± 40.30	133.31 ± 36.50	− 2.00	0.049
Upper-lower diameter of lung (cm)
Upper-lower diameter Insp (cm)	23.15 ± 2.48	21.80 ± 1.49	2.74	0.009
Upper-lower diameter Exp (cm)	19.00 ± 3.49	14.56 ± 1.45	7.65	P < 0.001
Diaphragmatic displacement (cm)	4.16 ± 2.02	7.24 ± 1.26	− 5.81	P < 0.001
Diaphragm thickness (cm)
Thickness Insp (cm)	6.04 ± 1.07	7.04 ± 1.02	− 3.34	0.001
Thickness Exp (cm)	4.69 ± 0.61	4.30 ± 0.78	2.11	0.038
Diaphragm thickening fraction	29.08 ± 16.57	66.11 ± 22.46	− 7.32	P < 0.001

Data are expressed as means ± SD except where otherwise noted
COPD, chronic obstructive pulmonary disease; Insp, inspiration; Exp, expiration; SD, standard deviation

ISSN: 1471-2466