Characters | Success group (n = 59) | Failure group (n =37) | p-Value |
---|---|---|---|
Baseline | |||
Age (years) | 64.00 [54.50–74.00] | 67.00 [58.00–77.00] | 0.515 |
Male (%) | 35 (59.3) | 25 (67.6) | 0.551 |
APACHE II score | 20.00 [18.00–25.00] | 18.00 [13.00–21.00] | 0.002 |
Temperature (℃) | 37.00 [36.65–37.30] | 37.00 [36.60–37.30] | 0.979 |
Heart rate (bpm) | 96 [83–112] | 96 [82–115] | 0.827 |
Respiratory rate (bpm) | 18 [16–19] | 22 [17–26] | 0.001 |
Systolic pressure (mmHg) | 131 [123–141] | 130 [117–139] | 0.331 |
Diastolic pressure (mmHg) | 69 [64–72] | 69 [65–71] | 0.656 |
PaO2 / FiO2 ratio (mmHg) | 252.50 [212.85–280.70] | 241.40 [216.70–280.20] | 0.665 |
Support pressure on SBT (cmH2O) | 7.00 [6.00–8.00] | 7.00 [6.00–8.00] | 0.83 |
Positive end expiratory pressure (cmH2O) | 5.00 [5.00–5.00] | 5.00 [5.00–5.00] | 0.76 |
Ventilator days before SBT (days) | 4.00 [3.00–5.50] | 8.00 [6.00–9.00] |  < 0.001 |
Type of ICU admission (%) | 0.988 | ||
Medical | 29 (49.2) | 18 (48.6) | Â |
Elective surgical | 18 (30.5) | 11 (29.7) | Â |
Urgent surgical | 12 (20.3) | 8 (21.6) | Â |
Comorbidity | |||
Hypertension (%) | 19(32.2%) | 12 (32.4%) |  > 0.999 |
Diabetes (%) | 9 (15.3) | 6 (16.2) |  > 0.999 |
Chronic pulmonary disease (%) | 8 (13.6) | 5 (13.5) |  > 0.999 |
Chronic heart failure (%) | 7 (11.9) | 4 (10.8) |  > 0.999 |
Malignant solid tumor (%) | 7 (11.9) | 4 (10.8) |  > 0.999 |
Chronic kidney disease (%) | 6 (10.2) | 3 (8.1) |  > 0.999 |
Others (%) | 4 (6.8) | 2 (5.4) |  > 0.999 |
Etiology of mechanical ventilation |  > 0.999 | ||
Postsurgical respiratory failure | 8 (13.6) | 4 (10.8) | Â |
Sepsis | 18 (30.5) | 11 (29.7) | Â |
ARDS | 9 (15.3) | 6 (16.2) | Â |
AECOPD | 9 (15.3) | 6 (16.2) | Â |
Acute left heart failure | 6 (10.2) | 4 (10.8) | Â |
Trauma | 2 (3.4) | 1 (2.7) | Â |
Others | 8 (13.6) | 4 (10.8) | Â |
Outcomes | |||
Failed SBT | – | 30 (81.1) | NA |
Reintubation in 48 h | – | 4 (10.8) | NA |
Death within 7 days of extubation | – | 3 (8.1) | NA |
NPPV | 5 (8.5) | 8 (21.6) | 0.127 |
High-flow oxygen therapy | 10 (16.9) | 16 (43.2) | 0.01 |
28-day mortality | 8 (13.6) | 16 (43.2) | 0.002 |