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Table 3 Demographics, laboratory test, type of ICU admission, comorbidity, etiology of mechanical ventilation, and treatment in the examined patients

From: Comparison of assessment of diaphragm function using speckle tracking between patients with successful and failed weaning: a multicentre, observational, pilot study

Characters

Success group (n = 59)

Failure group (n =37)

p-Value

Baseline

Age (years)

64.00 [54.50–74.00]

67.00 [58.00–77.00]

0.515

Male (%)

35 (59.3)

25 (67.6)

0.551

APACHE II score

20.00 [18.00–25.00]

18.00 [13.00–21.00]

0.002

Temperature (℃)

37.00 [36.65–37.30]

37.00 [36.60–37.30]

0.979

Heart rate (bpm)

96 [83–112]

96 [82–115]

0.827

Respiratory rate (bpm)

18 [16–19]

22 [17–26]

0.001

Systolic pressure (mmHg)

131 [123–141]

130 [117–139]

0.331

Diastolic pressure (mmHg)

69 [64–72]

69 [65–71]

0.656

PaO2 / FiO2 ratio (mmHg)

252.50 [212.85–280.70]

241.40 [216.70–280.20]

0.665

Support pressure on SBT (cmH2O)

7.00 [6.00–8.00]

7.00 [6.00–8.00]

0.83

Positive end expiratory pressure (cmH2O)

5.00 [5.00–5.00]

5.00 [5.00–5.00]

0.76

Ventilator days before SBT (days)

4.00 [3.00–5.50]

8.00 [6.00–9.00]

 < 0.001

Type of ICU admission (%)

0.988

Medical

29 (49.2)

18 (48.6)

 

Elective surgical

18 (30.5)

11 (29.7)

 

Urgent surgical

12 (20.3)

8 (21.6)

 

Comorbidity

Hypertension (%)

19(32.2%)

12 (32.4%)

 > 0.999

Diabetes (%)

9 (15.3)

6 (16.2)

 > 0.999

Chronic pulmonary disease (%)

8 (13.6)

5 (13.5)

 > 0.999

Chronic heart failure (%)

7 (11.9)

4 (10.8)

 > 0.999

Malignant solid tumor (%)

7 (11.9)

4 (10.8)

 > 0.999

Chronic kidney disease (%)

6 (10.2)

3 (8.1)

 > 0.999

Others (%)

4 (6.8)

2 (5.4)

 > 0.999

Etiology of mechanical ventilation

 > 0.999

Postsurgical respiratory failure

8 (13.6)

4 (10.8)

 

Sepsis

18 (30.5)

11 (29.7)

 

ARDS

9 (15.3)

6 (16.2)

 

AECOPD

9 (15.3)

6 (16.2)

 

Acute left heart failure

6 (10.2)

4 (10.8)

 

Trauma

2 (3.4)

1 (2.7)

 

Others

8 (13.6)

4 (10.8)

 

Outcomes

Failed SBT

–

30 (81.1)

NA

Reintubation in 48 h

–

4 (10.8)

NA

Death within 7 days of extubation

–

3 (8.1)

NA

NPPV

5 (8.5)

8 (21.6)

0.127

High-flow oxygen therapy

10 (16.9)

16 (43.2)

0.01

28-day mortality

8 (13.6)

16 (43.2)

0.002

  1. Data are presented as median with interquartile range or frequencies with percentages. APACHE II Acute Physiology, Age, Chronic Health Evaluation II; PaO2 Partial arterial oxygen pressure; FiO2 Fraction of inspired oxygen; ARDS Acute Respiratory Distress Syndrome; AECOPD Acute exacerbation of chronic obstructive pulmonary disease; NMBAs Neuromuscular blocking agents; SBT Spontaneous breathing trial; NPPV Non-invasive positive pressure ventilation