Table 4 Comparison of clinical characteristics with CEA and Cyfra21-1 expression in serum samples
From: Identification of serum MiRNAs as candidate biomarkers for non-small cell lung cancer diagnosis
Characteristics | Number | CEA (ng/mL) | Cyfra21-1 (ng/mL) | ||||
|---|---|---|---|---|---|---|---|
mean (range) | Z score | p value | mean (range) | Z score | p value | ||
Disease status | Â | Â | Â | Â | Â | Â | Â |
 Cancer | 78 | 2.925 (1.237–8.607) | 3.534 |  < 0.001 | 4.200 (1.307–11.48) | 3.607 |  < 0.001 |
 Noncancerous | 44 | 1.650 (0.830–2.740) |  |  | 2.280 (0.815–2.930) |  |  |
Histological type | Â | Â | Â | Â | Â | Â | Â |
 SCC | 40 | 2.210 (1.195–3.567) | 2.409 | 0.016 | 4.620 (1.975–17.94) | 2.069 | 0.039 |
 ADC | 38 | 4.475 (1.560–16.39) |  |  | 3.255 (1.032–7.590) |  |  |
Tumor stage | Â | Â | Â | Â | Â | Â | Â |
 I + II | 20 | 1.685 (1.115–3.130) | 2.552 | 0.011 | 1.435 (0.660–4.830) | 2.718 | 0.007 |
 III + IV | 58 | 3.400 (1.587–10.85) |  |  | 4.785 (2.052–14.69) |  |  |