Table 2 Comparison of PFT results among the three groups and ROC analyses for pulmonary cGVHD
PFT parameters (median with rage) | Group A | Group B | Group C | P value* | ROC§ | Cut-off value | Specificity (%) | Sensitivity (%) | P value of ROC |
|---|---|---|---|---|---|---|---|---|---|
FVC/pred (%) | 94.9 (80.7–109.8) | 95.2 (43.7–136.3) | 94.1 (38.8–129.3) | 0.200 | 0.554 | 107.15 | 0.831 | 0.385 | 0.502 |
FEV1/pred (%) | 93.7 (38.3–111.2) | 98.5 (18.4–139.9) | 97 (29.2–138) | 0.544 | 0.537 | 82.65 | 0.847 | 0.308 | 0.648 |
FEV1/FVC (%) | 83.82 (38.95–95.6) | 86.12 (25.15–99.2) | 86.22 (8.01–100) | 0.093 | 0.679 | 83.935 | 0.663 | 0.692 | 0.027 |
PEF/pred (%) | 83.1 (9.8–110.5) | 93.05 (20.8–145.8) | 92.9 (9.8–156.3) | 0.022 | 0.72 | 88.25 | 0.627 | 0.769 | 0.006 |
MEF75/pred (%) | 87.9 (12.6–107.5) | 96.35 (5–166.6) | 98.4 (4.6–160.1) | 0.037 | 0.701 | 90.35 | 0.663 | 0.769 | 0.013 |
MEF50/pred (%) | 81 (8.4–103.6) | 90.15 (4.2–170.4) | 92.6 (8.3–213.3) | 0.096 | 0.668 | 103.65 | 0.343 | 1 | 0.037 |
MEF25/pred (%) | 77.3 (7.9–101.2) | 81 (5.3–201.8) | 84.6 (7.3–563) | 0.183 | 0.626 | 101.25 | 0.303 | 1 | 0.119 |
MMEF/pred (%) | 79.2 (9.1–110.2) | 91.55 (4.8–170.4) | 92.5 (8.6–202.6) | 0.075 | 0.67 | 83.95 | 0.646 | 0.692 | 0.035 |
MVV/pred (%) | 94.1 (44.2–101.8) | 94.8 (22.9–150.5) | 93.5 (0–151.8) | 0.103 | 0.623 | 101.85 | 0.321 | 1 | 0.143 |