The role of platelet-related parameters for the prediction of NAFLD in OSAHS patients

Chen, Menglan; Wang, Biying; Huang, Jiefeng; Zhao, Jianming; Chen, Jia; Chen, Gongping

doi:10.1186/s12890-022-02291-6

BMC Pulmonary Medicine

Table 5 Areas under the receiver-operating characteristic curves for each parameter for predicting non-alcoholic fatty liver disease

From: The role of platelet-related parameters for the prediction of NAFLD in OSAHS patients

Parameters	Area under the ROC curve	95% CI	P	SE	Cut off value	Sensitivity (%)	Specificity (%)
All subjects (n = 351)
WBC/MPV	0.672	(0.602, 0.741)	0.000	0.035	0.725	0.613	0.708
PLR	0.679	(0.618, 0.740)	0.000	0.031	91.225	0.369	0.972
The combination of WBC/MPV and PLR	0.743	(0.684, 0.801)	0.000	0.030	0.790	0.669	0.694
FLI	0.770	(0.708, 0.831)	0.000	0.031	2.101	0.663	0.775
APRI	0.632	(0.563, 0.700)	0.001	0.035	0.299	0.337	0.903
BMI < 28 kg/m² (n = 214)
WBC/MPV	0.664	(0.582, 0.746)	0.000	0.042	0.720	0.618	0.719
PLR	0.683	(0.609, 0.756)	0.000	0.038	97.090	0.420	0.333
The combination of WBC/MPV and PLR	0.753	(0.684, 0.822)	0.000	0.035	0.733	0.688	0.736
FLI	0.742	(0.663, 0.820)	0.000	0.040	1.265	0.675	0.732
APRI	0.604	(0.520, 0.687)	0.020	0.043	0.259	0.465	0.184
BMI ≥ 28 kg/m² (n = 137)
WBC/MPV	0.653	(0.511, 0.795)	0.054	0.072	0.726	0.623	0.667
PLR	0.631	(0.513, 0.748)	0.099	0.060	91.545	0.402	1.000
The combination of WBC/MPV and PLR	0.674	(0.536, 0.812)	0.028	0.070	0.859	0.779	0.533
FLI	0.764	(0.636, 0.892)	0.001	0.065	6.137	0.590	0.866
APRI	0.688	(0.562, 0.814)	0.018	0.064	0.290	0.426	0.933
Age < 60 years (n = 245)
WBC/MPV	0.717	(0.634, 0.800)	0.000	0.042	0.726	0.653	0.783
PLR	0.635	(0.560, 0.710)	0.004	0.038	91.395	0.362	0.957
The combination of WBC/MPV and PLR	0.729	(0.652, 0.806)	0.000	0.039	0.760	0.779	0.630
FLI	0.774	(0.695, 0.853)	0.000	0.040	2.101	0.739	0.756
APRI	0.632	(0.548, 0.716)	0.005	0.043	0.261	0.472	0.761
Age ≥ 60 years (n = 106)
WBC/MPV	0.572	(0.445, 0.669)	0.271	0.065	0.591	0.813	0.385
PLR	0.760	(0.663, 0.857)	0.000	0.050	102.380	0.500	0.923
The combination of WBC/MPV and PLR	0.786	(0.692, 0.880)	0.000	0.048	0.822	0.650	0.846
FLI	0.751	(0.640, 0.862)	0.000	0.057	0.690	0.875	0.538
APRI	0.634	(0.515, 0.753)	0.040	0.061	0.289	0.400	0.923

PLR platelet to lymphocyte ratio, WBC/MPV white blood cell count to mean platelet volume ratio, FLI fatty liver index, APRI AST platelet ratio index, CI Confidence interval, SE Standard error

Back to article page

ISSN: 1471-2466

Contact us

Submission enquiries: bmcpulmonarymedicine@biomedcentral.com
General enquiries: ORSupport@springernature.com