Table 2 Clinical characteristics, laboratory findings and prognosis of PJP and non-PJP patients
Characteristics (n [%]or median [IQR]) | PJP patients (N = 33) | Non-PJP patients (N = 34) | Statistical value | P value |
|---|---|---|---|---|
Clinical symptoms Cough | 21 (63.64) | 27 (79.41) | 2.051 | 0.152 |
Expectoration | 15 (45.45) | 19 (55.88) | 0.729 | 0.393 |
Fever | 25 (75.76) | 14 (41.18) | 8.232 | 0.004 |
Dyspnea | 25 (75.76) | 17 (50.00) | 4.750 | 0.029 |
White blood cells (×109/L) | 7.90 (6.20, 10.80) | 10.15 (7.68, 12.28) | − 1.825 | 0.068 |
Neutrophils (×109/L) | 6.92 (5.30, 8.95) | 7.85 (5.23, 87.33) | − 0.884 | 0.377 |
Lymphocytes (×109/L) | 1.00 (0.40, 2.70) | 1.50 (0.95, 6.30) | − 2.015 | 0.044 |
PCT (ng/mL) | 0.42 (0.27, 2.14) | 0.24 (0.10, 3.29) | − 1.519 | 0.129 |
ESR (mm/h) | 66.00 (43.25, 82.75) | 63.00 (35.00, 81.50) | − 0.341 | 0.733 |
CRP (mg/L) | 44.30 (19.05,137.50) | 53.20 (16.37, 156.00) | − 0.083 | 0.934 |
ALB (g/L) | 29.00 (24.00, 34.00) | 32.50 (29.00, 35.00) | − 12.571 | 0.000 |
LDH (U/L) | 461.50 (283.25, 681.25) | 196.50 (301.00, 378.00) | 4.346 | 0.000 |
> 250 | 28 (84.85) | 19 (55.88) | 6.710 | 0.010 |
Serum BDG (ng/L) | 53.3 (7.75, 310.9) (n = 26) | 9.00 (5.00, 25.00) (n = 23) | − 2.395 | 0.017 |
> 80 | 12 (46.15) | 3 (13.04) | 6.299 | 0.012 |
> 200 | 10 (38.46) | 0 (0) | 8.873 | 0.003 |
Lymphocyte subsets (/µl) |  |  |  |  |
CD3+ T cell number | 419.00 (213.00, 1014.50) | 602.00 (326.00, 887.75) | − 0.934 | 0.350 |
CD4+ T cell number | 195.00 (107.00, 416.50) | 321.00 (133.50, 473.25) | − 1.329 | 0.184 |
< 300 | 21 (63.64) | 16 (47.06) | 1.861 | 0.172 |
< 200 | 17 (51.52) | 12 (35.29) | 1.795 | 0.180 |
CD8+ T cell number | 176.00 (79.50, 403.00) | 235.50 (107.50, 374.00) | − 0.671 | 0.502 |
CD4+ T cell /CD8+ T cell | 1.03 (0.55, 2.27) | 1.64 (0.71, 2.11) | − 0.596 | 0.551 |
NK cell number | 30.00 (10.50, 103.75) | 72.50 (26.25, 153.75) | − 1.691 | 0.091 |
CD19+B cell number | 55.00 (13.00, 113.00) | 113.00 (32.50, 154.75) | − 1.518 | 0.129 |
Humoral immunity (g/L) | (n = 22) | (n = 26) |  |  |
IgG | 8.33 (7.02, 14.85) | 12.90 (9.41, 15.68) | − 1.428 | 0.153 |
IgA | 1.79 (1.29,2.91) | 2.16 (1.59, 2.95) | − 1.076 | 0.282 |
IgM | 0.79 (0.42, 1.51) | 0.96 (0.70, 1.51) | − 1.397 | 0.162 |
Complement C3 | 1.07 (1.07, 1.36) | 1.16 (0.88, 1.36) | − 1.283 | `0.199 |
Complement C4 | 0.21 (0.18, 0.27) | 0.25 (0.22, 0.33) | − 1.738 | 0.082 |
GMS staining (+) | 4 (12.12) | 0 (0) | 2.490 | 0.115 |
Admission to ICU | 9 (27.27) | 15 (44.12) | 2.067 | 0.151 |
Invasive mechanical ventilation | 10 (30.30) | 10 (29.41) | 0.006 | 0.936 |
Severe pneumonia | 18 (54.55) | 15 (44.12) | 0.729 | 0.393 |
Respiratory failure | 26 (78.79) | 21 (61.76) | 2.318 | 0.128 |
Septic shock | 4 (12.12) | 5 (14.71) | 0.000 | 1.000 |
MODS | 3 (9.09) | 1 (2.94 ) | 0.299 | 0.585 |
30-day mortality | 9 (27.27) | 9 (26.47) | 0.005 | 0.941 |