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Fig. 1 | BMC Pulmonary Medicine

Fig. 1

From: FAM83B promotes the invasion of primary lung adenocarcinoma via PI3K/AKT/NF-κB pathway

Fig. 1

Expression of FAM83B in pan-carcinoma and primary LUAD. A: The TCGA database shows that FAM83B is upregulated in multiple types of carcinomas. B: The expression level of FAM83B mRNA between normal pulmonary tissues and LUAD. The Wilcoxon rank sum test showed that the unpaired sample of 59 normal tissues and 513 tumors showed that the expression of FAM83B in tumors were higher than those in normal samples and the median difference between the two groups was 0.824 (0.669–0.98) with statistical significance (P < 0.001); Among them, 57 paired samples showed that FAM83B in tumor was higher than that in normal lung tissue, and the median difference between the two groups was 0.582 (0.395–0.89), the difference was statistically significant (P < 0.001) C: The expression of FAM83B protein in primary LUAD was higher than that in the normal pulmonary tissues. DF: Analysis of Kaplan Meier plot showed that the OS, DSS and PFI were significantly lower in high expression group than those in low expression queue. ***P < 0.001

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