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Table 4 Univariate and multivariate Cox proportional hazards analyses after PSM

From: Postoperative survival of pulmonary invasive mucinous adenocarcinoma versus non-mucinous invasive adenocarcinoma

Variables

Univariate analysis

Multivariable analysis

HR

95% CI

p

HR

95% CI

p

Age (years)

≤ 65

Reference

     

> 65

1.98

1.7–2.31

< 0.0001

1.85

1.57–2.18

 < 0.0001

Chemotherapy

No

Reference

     

Yes

1.51

1.26–1.8

< 0.0001

0.91

0.73–1.13

0.3975

Grade

I

Reference

     

II

1.35

1.12–1.63

0.002

1.17

0.96–1.42

0.1219

III

2.09

1.45–3.01

< 0.0001

1.67

1.12–2.48

0.0116

Unknown

1.1

0.91–1.33

0.329

1.02

0.84–1.24

0.8572

IMA

No

Reference

     

Yes

1.04

0.87–1.24

0.652

   

Laterality

Left

Reference

     

Right

1

0.86–1.15

0.971

   

Location

Upper

Reference

     

Lower

0.97

0.83–1.13

0.686

1.04

0.89–1.21

0.6488

Middle

0.88

0.62–1.25

0.475

1.06

0.74–1.52

0.7464

Other

1.9

1.21–3

0.006

1.49

0.92–2.41

0.1021

Marital status

Single

Reference

     

Divorced

0.77

0.58–1.04

0.087

   

Married

0.87

0.73–1.03

0.096

   

N

N0

Reference

     

N1

1.92

1.38–2.68

< 0.0001

1.04

0.63–1.73

0.8749

N2

2.51

1.82–3.47

< 0.0001

1.06

0.29–3.84

0.9257

Operation

Lobectomy

Reference

     

Lobectomy extended

1.67

1.15–2.43

0.007

1.26

0.86–1.86

0.2348

Other sublobar

1.73

0.9–3.34

0.102

1.15

0.57–2.3

0.6961

Pneumonectomy

1.51

0.92–2.49

0.101

0.88

0.52–1.48

0.6188

Segmentectomy

1

0.58–1.74

0.988

1.28

0.74–2.24

0.3779

Wedge

0.95

0.69–1.31

0.752

1.15

0.82–1.6

0.4167

Race

Black

Reference

     

Other

0.65

0.44–0.94

0.024

0.54

0.36–0.79

0.0014

White

1.09

0.85–1.39

0.488

0.95

0.74–1.23

0.7218

Radiation

No

Reference

     

Yes

2.49

1.84–3.37

< 0.0001

1.54

1.09–2.18

0.0155

Sex

Male

Reference

     

Female

0.55

0.48–0.64

< 0.0001

0.64

0.55–0.75

< 0.0001

Size

1.01

1.01–1.01

< 0.0001

1

1–1

0.5011

Stage

IA1

Reference

     

IA2

1.59

0.95–2.66

0.08

1.54

0.92–2.59

0.1016

IA3

2.29

1.39–3.76

0.001

2.19

1.32–3.62

0.0024

IB

3.36

2.05–5.51

< 0.0001

2.63

1.13–6.13

0.0245

IIA

3.01

1.79–5.05

< 0.0001

2.32

0.98–5.5

0.0562

IIB

5.43

3.33–8.85

< 0.0001

5.05

2.03–12.59

0.0005

IIIA

7.61

4.68–12.38

< 0.0001

4.94

1.29–18.99

0.0199

IIIB

12.07

6.15–23.7

< 0.0001

10.37

0.97–110.58

0.0527

T

T1

Reference

     

T2

1.7

1.41–2.05

< 0.0001

1.17

0.59–2.3

0.658

T3

2.81

2.28–3.46

< 0.0001

0.9

0.41–2.01

0.8048

T4

4.21

3.43–5.18

 < 0.0001

1.51

0.44–5.17

0.5135

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BMC Pulmonary Medicine

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