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Table 6 Results of univariate analysis to identify factors associated with peak VD/Vt in patients with normal exercise capacity (n = 48)

From: Evaluation of long-term sequelae by cardiopulmonary exercise testing 12 months after hospitalization for severe COVID-19

 

r2

p value

Patient’s characteristics

Age (years)

0.13

0.01

Sexe

0.07

0.07

BMI (kg/m2)

0.03

0.2

Length of ICU stay (days)

0.24

0.10

Pulmonary embolism

0.01

0.3

CRP (mg/ml)

0.004

0.6

Fibrinogen (g/L)

0.009

0.5

D-Dimers (ng/ml)

0.12

0.02

Creatinine (mg/dl)

0.07

0.07

Total WBC count (109/L)

0.03

0.2

Pulmonary function tests

FEV1 (% predicted)

0.08

0.05

FEV1 (L)

0.02

0.3

VC (% predicted)

0.03

0.2

VC (L)

0.002

0.7

DLCO cor (%predicted)

 − 0.15

0.01

DLCO cor (ml/min/mmHg)

 − 0.06

0.09

CPET at AT

PetCO2

 − 0.53

0.0001

%VO2 peak predicted

 − 0.11

0.46

CPET at peak

V′O2 peak, ml/kg/min %predicted

 − 0.17

0.25

V′O2 peak, ml/kg/min

PetCO2

 − 0.43

0.003

V′E/VO2 ratio

0.48

0.0006

V′E/V′CO2 ratio

0.58

 < 0.0001

V′E/V′CO2 slope

0.53

0.0001

V′O2 pulse (%predicted)

0.1

0.52

pO2 (mmHg)

 − 0.13

0.01

pCO2 (mmHg)

0.004

0.8

P(A-a) (mmHg)

0.46

0.01

  1. BMI, Body mass index; ICU, Intensive care unit; CRP, C-reactive protein; WBC, White blood cell; FEV1, Forced expiratory volume at 1st second; FVC, Forced vital capacity; TLC, Total lung capacity; DLCOcor, Lung transfer for carbon monoxide; KCO, Carbon monoxide transfer coefficient; PetCO2, End-tidal pressure of CO2; RER, Respiratory exchange ratio; V′O2, Oxygen uptake; V′E/V′O2 and V′E/V′CO2, Ventilatory equivalents for oxygen and carbon dioxide; HR, Heart rate; PcapO2, Capillary arterialized pO2; PcapCO2, Capillary arterialized pCO2;P(A-a)O2, Alveolar-arterial O2 gradient
  2. Bold represents p-values that are statistically significant
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BMC Pulmonary Medicine

ISSN: 1471-2466

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