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Table 2 Summarized treatment course of the patient

From: Pulmonary veno-occlusive disease in Sjogren's syndrome: a case report

Time of admission

2018.11

2019.3

2021.6

RVSPa (mmHg)

60

69

78

PAa(mm)

27

30

30

EFa (%)

62

53

52

TAPSE a(mm)

17

12

10

RV a (mm)

48

53

60

NT-proBNP(ng/ml, pre-treatment)

2482

2572

3445

NT-proBNP(ng/ml, post-treatment)

780

650

846

Functional class (NYHA, pre-treatment)

III

III

III

Functional class (NYHA, post-treatment)

II

II

II

PAH-target drugs

Tadalafil (10 mg,qd)

Tadalafil (20 mg,qd)

Macitentan(10 mg,qd)

Tadalafil (20 mg,qd)

Macitentan(10 mg,qd)

  1. abased echocardiography; EF was measured for the left ventricle; RV were determined by subxiphoid four chamber section; PA were measured by short axis section of aorta; EF: ejection function; NYHA: New York Heart Association; NT-proBNP N-terminal pro-brain natriuretic peptide; PA: pulmonary artery; PAH: pulmonary artery hypertension; RV: right ventricular; RVSP: right ventricular systolic pressure; TAPSE: Tricuspid annular plane systolic excursion