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Table4 Characterization of maternal mortality in pulmonary hypertension

From: Effect of multidisciplinary team (MDT) centred on pregnant women with pulmonary hypertension on treatment and outcomes of pregnancy

Patients

Etiology

sPAP

(mmHg)

Delivery timing

(weeks)

Delivery mode

Anesthesia

Rescue therapy

Timing after delivery

Cause of death

1

PDA

105

34

Urgent cesarean

Epidural-

dopamine + adrenaline

 + ventilator

3 days

Severe preeclampsia, heart failure associated with multiple organ failure

2

PDAa

89

35

Urgent cesarean

General-

nitric oxide + epinephrine + dopamine isoproterenol + 

norepinephrineventilator + CPR

10 days

Persistent hypoxemia, circulatory collapse and hypoxic encephalopathy

3

VSD

57

33

Urgent cesarean

General-

epinephrine + dopamine + ventilator + CPR

within 24 h

Multiple organ failure, postpartum hemorrhage(1500 ml)

4

ASD

87

38

Urgent cesarean

General-

dopamine + epinephrine

 + dopamine + ventilator

10 days

Severe preeclampsia, circulatory collapse, hypoxic encephalopathy

5

VSDb

84

33

Planned cesarean

Epidural-

Nebulized iloprost + Nitric oxide + defibrillation

2 days

Sudden ventricular fibrillation with RV systolic pressure as high as 132 mmHg

  1. aleft-to-right shunting developed into right-to-left shunting or bidirectional shunting(Eisenmenger syndrome;bpostoperative pulmonary arterial hypertension; ASD atrial septal defect; PDA patent ductus arteriosus; VSD ventricular septal defect; sPAP pulmonary artery systolic pressure; CPR cardiopulmonary resuscitation