Fig. 3From: Primary diffuse Rosai-Dorfman disease in central airway: a case report and literature reviewHistopathological and immunohistochemical characteristics of the RDD patient. A Numerous lymphocytes, plasma cells, neutrophils and a few eosinophils infiltrated in the bronchial submucosa (HE 10 × 10). B A few large histocytes were scattered in the mass (HE 10 × 40). C The large histocytes showed S-100 protein positive with emperipolesis phenomenon (IHC × 400). D HLA-DR positive in the large histiocytes (IHC × 400)Back to article page