Table 2 Laboratory examination and pulmonary function test of COPD-PH and COPD-NPH patients

TB,umol/L

9.55(6.73,12.35)

10.50(8.70,14.20)

0.035

13.10(10.70,16.15)^†

17.65(11.65,25.05)^§

0.008

DB, umol/L

2.90(2.20,4.10)

3.80(3.10,4.75)

0.007

2.70(2.10,3.45)

4.55(2.45,6.28)

0.022

IB, umol/L

5.90(4.50,9.23)

6.80(5.50,9.40)

0.049

10.10(8.50,13.25)^†

13.50(8.75,19.00)^§

0.021

ALT, IU/L

21.50(12,31.25.00)

15.00(10,27.50)

0.786

18.00(12.00,28.00)^†

18(13.00,24.50)

0.200

AST, IU/L

20.00(15.705,25)

19.00(15.50,26.00)

0.403

20.00(17.00,27.00)

22.00(19.00,29.00)

0.651

TP, g/L

65.55(60.35,68.45)

63.80(62.45,66.85)

0.638

65.20(61.65,68.25)

63.80(58.28,68.83)

0.087

ALB,g/L

39.67 ± 3.87

39.16 ± 3.36

0.496

39.07 ± 3.63

36.66 ± 3.77^§

0.001

Cr, umol/L

74.00(60.75,87.00)

71.00(57.50,87.50)

0.838

71.00(62.50,84.50)

71.00(65.00,89.00)

0.769

BNP, pg/mL

76.50(46.50,143.75)

211.00(125.50,1085.00)

< 0.001

37.00(21.50,118.00)^†

234.50(53.50,396.50)^§

< 0.001

CRP, mg/mL

5.12(2.61,12.50)

8.92(3.31,19.85)

0.100

2.56(0.67,6.90)^†

3.47(1.82,6.51)§

0.054

PCT, ng/mL

0.040(0.020,0.073)

0.030(0.020,0.050)

0.755

0.037(0.026,0.049)

0.041(0.026,0.050)

0.786

Hb, g/L

136.67 ± 19.07

137.89 ± 23.60

0.769

167.13 ± 27.27^†

172.41 ± 30.94^§

0.354

PLT, x10^9/L

192.10 ± 73.12

163.11 ± 62.47

0.042

165.97 ± 59.83^†

146.84 ± 51.81

0.074

WBC, x10^12/L

7.16(5.74,8.77)

6.75(5.94,7.69)

0.247

5.54(4.59,7.07)^†

5.18(4.50,6.51)^§

0.511

NEUT, x10^9/L

4.46(3.30,6.22)

4.49(3.63,5.51)

0.995

4.79(3.45,5.59)^†

3.56(2.77,4.47)^§

0.932

LYx10^9/L

1.61 ± 0.72

1.35 ± 0.52

0.029

1.41 ± 0.47

1.23 ± 0.52

0.064

PH

7.41 ± 0.03

7.42 ± 0.05

0.196

7.42 ± 0.04

7.42 ± 0.04

0.44

PaO₂, mmHg

80.80(67.33,98.03)

80.70(68.90,120.85)

0.821

77.00(59.00,98.50)^†

63.50(54.75,77.25)^§

0.011

PaCO₂, mmHg

43.95 ± 7.76

42.41 ± 10.34

0.393

39.82 ± 6.69^†

44.91 ± 8.66

0.002

SaO₂, %

97.20(94.93,98.43)

96.20(94.60,99.20)

0.767

96.00(91.00,98.00)^†

92.00(88.00,95.25)^§

0.013

HCO₃⁻, mmol/L

25.95(24.18,30.83)

26.70(23.80,29.05)

0.671

25.20(22.85,27.20)

28.50(25.78,30.20)^§

0.001

FEV₁, % predicted

46.45(33.10,58.73)

47.50(31.60,66.35)

0.27

57.40(37.40,79.35)

40.50(26.63,50.75)^§

0.008

FEV₁/FVC, % predicted

45.63(38.45,60.33)

48.22(40.72,63.20)

0.278

58.94(52.48,63.66)^†

55.18(44,35,61.23)

0.044

VC, % predicted

73.86 ± 18.61

73.63 ± 19.69

0.952

71.95 ± 23.14

62.98 ± 24.49

0.054

GOLD stages (FEV₁, % predicted), n%

0.08

< 0.001

GOLD1 + 2(≥ 50% predicted)

28(35.40)

19(52.80)

27(60.00)^†

18(26.50)^§

GOLD3 + 4(< 50% predicted)

51(64.60)

17(47.20)

18(40.00)

50(73.50)