Fig. 5

Risk assessment and survival differences in the PAH clusters. Risk assessment strata distribution and overall survival was compared between the study participant clusters with and log-rank test, respectively. P values were adjusted for multiple testing with Benjamini–Hochberg method. Numbers of individuals assigned to the clusters are presented in the Y axes or in the plot legends. A – E Risk assessment strata frequencies in the PAH clusters presented in stack plots. All differences were significant with p < 0.001. F Differences in overall survival in the PAH clusters visualized in Kaplan–Meier plots. P values are indicated in the plots. Numbers of complete observations and deaths are shown in the plot captions. FPHR 3p: French Pulmonary Hypertension Registry 3 parameter score, FPHR 4p: French Pulmonary Hypertension Registry 4 parameter score, COMPERA: Comparative, Prospective Registry of Newly Initiated Therapies for Pulmonary Hypertension score, mRASP: modified Risk Assessment Score of PAH; int.: intermediate