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Fig. 1 | BMC Pulmonary Medicine

Fig. 1

From: The presence of circulating genetically abnormal cells in blood predicts risk of lung cancer in individuals with indeterminate pulmonary nodules

Fig. 1

Representative fluorescence microscopy images from the LungLB™ test demonstrating (A) a normal WBC with 2 spots in the Red (3p22.1), Green (3q29), Aqua (10cen), and Gold (10q22.3) color channels, (B) a CGAC, indicated by the white arrow, with an extra spot in the Red and Green channels, (C) an Advanced CGAC with 4 spots each in the Red and Green channels (4 × 2 Advanced CGAC), and (D) an Advanced CGAC with an extra spot in the Red and Green channels and a spot loss in the Gold and Aqua channels (Double Deletion Advanced CGAC). Cell nuclei are visualized in the DAPI channel.

Abbreviations: CGAC, circulating genetically abnormal cell; DAPI, 4′,6-diamidino-2-phenylindole; WBC, white blood cell.

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BMC Pulmonary Medicine

ISSN: 1471-2466

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