Variables | No mutation n = 963 | Mutation n = 144 | Total n = 1,107 | p-value |
---|---|---|---|---|
Male, n (%) | 602 (62.1) | 91 (63.2) | 693 (62.6) | 0.875 |
Age, median (p25-p75) | 73.8 (67.6–79.9) | 73 (66.6–79.9) | 73.8 (67.4–79.9) | 0.428 |
Weight, median (p25-p75) | 65 (56–74) | 65 (56.5–75) | 65 (56–74) | 0.468 |
BMI, median (p25-p75) | 25.1 (22.1–28.7) | 25.2 (22.8–28.5) | 25.1 (22.2–28.6) | 0.410 |
Age at onset of symptoms, median (p25-p75) | 64 (55–70) | 63 (55–70) | 64 (55–70) | 0.971 |
Age at diagnosis, median (p25-p75) | 65 (58–72) | 65 (59–72) | 65 (58–72) | 0.972 |
Moderate exacerbations in the previous year, mean ± SD | 0.25 ± 0.65 | 0.20 ± 0.66 | 0.24 ± 0.65 | 0.424 |
Severe exacerbations in the previous year, mean ± SD | 0.09 ± 0.35 | 0.11 ± 0.28 | 0.10 ± 0.35 | 0.514 |
Comorbidities and exposure factors | ||||
HT, n (%) | 521 (54.1) | 78 (54.2) | 599 (54.1) | 0.988 |
Diabetes mellitus, n (%) | 119 (13.4) | 21 (14.6) | 140 (12.6) | 0.453 |
Heart failure, n (%) | 169 (17.5) | 18 (13.5) | 187 (16.9) | 0.131 |
Smoking, n (%) | 691 (71.7) | 108 (75) | 799 (72.2) | 0.418 |
Years smoking, median (p25-p75) | 38 (24–47) | 35 (20–45) | 38 (22–47) | 0.283 |
PY, median (p25-p75) | 30 (15–50) | 25 (10-49.5) | 30 (15–50) | 0.119 |
s-hand smoke, n (%) | 189 (19.6) | 25 (17.4) | 214 (19.3) | 0.517 |
Biomass, n (%) | 297 (30.8) | 34 (23.6) | 331 (29.9) | 0.077 |
Biomass index, median (p25-p75) | 90 (40–200) | 85 (60–160) | 90 (40–200) | 0.858 |
Tuberculosis, n (%) | 51 (5.3) | 12 (8.33) | 63 (5.7) | 0.142 |
Occupational smoke, n (%) | 117 (13.6) | 15 (10.9) | 132 (13.2) | 0.386 |