The PaO2/FiO2 is independently associated with 28-day mortality in patients with sepsis: a retrospective analysis from MIMIC-IV database

Table 3 Threshold effect analysis for the relationship between LnPaO₂/FiO₂ and 28-day mortality in patients with sepsis

Outcome:	OR (95% CI)	P-value
Fitting model using standard logistic regression model	0.72 (0.68, 0.81)	< 0.0001
Fitting model using two-piecewise linear model
5.30	0.37 (0.32, 0.43)	< 0.0001
≥ 5.30	1.53 (1.31, 1.80)	< 0.0001
Log-likelihood ratio test		< 0.001

ORs were adjusted for: sex, age at admission, ethnicity, Charlson Comorbidity Index, SOFA scores, the use of dexamethasone, methylprednisolone, cortisone, noradrenaline, dopamine, dobutamine, IVIG, the use of mechanical ventilation and RRT, the use of carbapenem, cephalosporins, penicillin, vancomycin, heart rate, respiratory rate, temperature and MAP

ISSN: 1471-2466