Table 2 Diagnostic tests used for patients admitted with CAP in the UK, France and Spain
Diagnostic test | Diagnostic tests considered categorised by patient immune status | Could this diagnostic test be omitted when the panels are used? | Median reported test turnaround time (hours) a | |||||
|---|---|---|---|---|---|---|---|---|
Immunocompetent | Immunocompromised | Panel 1 | Panel 3 | Panel 1 + 3 | UK | France | Spain | |
Adenovirus screen | N | Y | Y | N | Y | 24 | 8 | 48 |
Aspergillus serum antigen | N | Y | N | N | N | 36.5 | 16.5 | 72 |
BAL culture | Y | Y | N | N | N | 48 | 12 | 72 |
Blood culture | Y | Y | N | N | N | 48 | 24 | 72 |
Chlamydophila sp serology | Y | Y | N | N | N | 48 | 10 | 72 |
Chlamydophila sp PCR (respiratory sample) | Y | Y | N | N | N | 36 | 8 | 12 |
COVID-19 PCR | Y | Y | Y | N | Y | 4.5 | 5 | 12 |
Cryptococcus serum antigen | N | Y | N | N | N | 48 | 7.5 | 12 |
Cytomegalovirus PCR (BAL sample) | N | Y | N | N | N | 48 | 8 | 8 |
Cytomegalovirus PCR serum | N | Y | N | N | N | 48 | 8 | 8 |
Cytomegalovirus PCR (sputum sample) | N | Y | N | N | N | 48 | 8 | 8 |
Epstein-Barr Virus screen | N | Y | N | N | N | 48 | 7.5 | 48 |
Legionella culture (BAL sample) | Y | Y | N | N | N | 48 | 9 | 24 |
Legionella culture (sputum sample) | Y | Y | N | N | N | 48 | 9 | 24 |
Legionella PCR (BAL sample) | Y | Y | N | Y | Y | 48 | 9 | 10 |
Legionella PCR (pleural fluid sample) | Y | Y | N | Y | Y | 48 | 9 | 10 |
Legionella PCR (sputum sample) | Y | Y | N | Y | Y | 48 | 9 | 10 |
Legionella urinary antigen test | Y | Y | N | Y | Y | 24 | 7 | 4 |
Mycobacterium culture (BAL sample) | Y | Y | N | N | N | 72 | 12 | 72 |
Mycobacterium culture (sputum sample) | Y | Y | N | N | N | 72 | 12 | 72 |
Mycobacterium PCR | Y | Y | N | N | N | 48 | 9 | 4 |
Mycology culture (BAL sample) | N | Y | N | N | N | 48 | 12 | 72 |
Mycology culture (sputum sample) | N | Y | N | N | N | 48 | 12 | 72 |
Mycology PCR (BAL sample) | N | Y | N | N | N | 48 | 12 | 12 |
Mycology PCR (sputum sample) | N | Y | N | N | N | 48 | 12 | 12 |
Mycoplasma pneumoniae serology | Y | Y | Y | Y | Y | 48 | 12 | 48 |
Mycoplasma pneumoniae PCR (respiratory sample) | Y | Y | Y | Y | Y | 48 | 8 | 10 |
Nocardia culture | N | Y | N | N | N | 48 | 12 | 72 |
Non-tuberculous mycobacteriab PCR (BAL sample) | N | Y | N | N | N | 48 | 12 | 4 |
Pleural fluid culture | Y | Y | N | N | N | 48 | 24 | 48 |
Pneumocystis jirovecii IF (BAL sample) | N | Y | N | Y | Y | 36.5 | 10 | 72 |
Pneumocystis jirovecii IF (sputum sample) | N | Y | N | Y | Y | 36.5 | 10 | 72 |
Pneumocystis jirovecii PCR (BAL sample) | N | Y | N | Y | Y | 48 | 8 | 72 |
Pneumocystis jirovecii PCR (sputum sample) | N | Y | N | Y | Y | 48 | 8 | 72 |
Respiratory virus PCR screen (respiratory sample) | Y | Y | Y | N | Y | 36 | 8 | 48 |
Sputum culture | Y | Y | N | N | N | 48 | 24 | 72 |
Streptococcus pneumoniae urinary antigen test | Y | Y | N | Y | Y | 24 | 7 | 4 |