Circulating choline levels are associated with prognoses in patients with pulmonary hypertension: a cohort study

BMC Pulmonary Medicine

Table 2 Multivariate Cox analysis of choline and clinical outcomes in total PH patients

Variable	HR	95% CI	P
Choline	1.934	1.034–3.619	0.039
Age, years	1.003	0.984–1.021	0.781
NT-proBNP, pg/mL (categorical variable)	0.755	0.421–1.353	0.345
Creatinine, µM	1.002	1.000-1.005	0.035
PeakVO₂, mL/min/kg	0.880	0.805–0.962	0.008
6MWD, m	1.001	0.421–1.353	0.724

Plasma choline levels were put into the model as a categorical variable bounded by 50th percentile (12.6 µM). PH: pulmonary hypertension; NT-proBNP: N-terminal pro-brain natriuretic peptide; 6MWD: 6-minute walk distance

ISSN: 1471-2466