Table 1 Cohort description by EHR-Berlin ARDS phenotype
Features | Total | ARDS- | ARDS+ | P |
|---|---|---|---|---|
|  | N = 765 |  N = 594 |  N = 171 |  |
Demographics | Â | Â | Â | Â |
Age, years, mean (SD) | 57 (18) | 57 (19) | 57 (15) | 0.68 |
Male sex, N (%) | 471 (62%) | 347 (58%) | 124 (73%) | < 0.001 |
Race, N (%) | Â | Â | Â | 0.18 |
White | 478 (62%) | 372 (63%) | 106 (62%) | Â |
Black/African American | 116 (15%) | 100 (17%) | 16 (9%) | Â |
Asian | 99 (13%) | 80 (13%) | 19 (11%) | Â |
American Indian or Alaskan Native | 24 (3%) | 18 (3%) | 6 (4%) | Â |
Native Hawaiian/ Pacific Islander | 14 (2%) | 9 (2%) | 5 (3%) | Â |
Unknown | 34 (4%) | 15 (3%) | 19 (11%) | Â |
Ethnicity, N (%) | Â | Â | Â | 0.016 |
Not Hispanic | 539 (70%) | 435 (73%) | 104 (61%) | Â |
Hispanic | 176 (23%) | 127 (21%) | 49 (29%) | Â |
Unknown | 50 (7%) | 32 (5%) | 18 (11%) | Â |
Chronic comorbidities | Â | Â | Â | Â |
Diabetes, N (%) | 314 (41%) | 227 (38%) | 87 (51%) | 0.003 |
Chronic renal disease, N (%) | 202 (26%) | 157 (26%) | 45 (26%) | 0.98 |
Chronic heart failure, N (%) | 199 (26%) | 152 (26%) | 47 (27%) | 0.62 |
Chronic pulmonary disease, N (%) | 174 (23%) | 137 (23%) | 37 (22%) | 0.69 |
Illness severity at admission | Â | Â | Â | Â |
Intensive care unit, N (%) | 255 (34%) | 121 (20%) | 134 (79%) | < 0.001 |
Invasive mechanical ventilation, N (%) | 144 (19%) | 32 (5%) | 112 (65%) | < 0.001 |
Noninvasive mechanical ventilation, N (%) | 21 (3%) | 5 (1%) | 16 (9%) | < 0.001 |
High-flow oxygen, N (%) | 42 (5%) | 18 (3%) | 24 (14%) | < 0.001 |
Resource utilization outcomes | Â | Â | Â | Â |
Duration of invasive mechanical ventilation, days, median (IQR) | 0 (0–1) | 0 (0–0) | 10 (3–22) | < 0.001 |
ICU length of stay, days, median (IQR) | 0 (0–5) | 0 (0–1) | 13 (4–22) | < 0.001 |
Hospital length of stay, days, median (IQR) | 8 (4–19) | 6 (3–13) | 19 (10–28) | < 0.001 |