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Table 2 Performance of EHR-based strategies to define ARDS compared to manual Berlin reference standard

From: Evaluating construct validity of computable acute respiratory distress syndrome definitions in adults hospitalized with COVID-19: an electronic health records based approach

 

EHR-Berlin definition

Diagnosis code (J80)

Diagnosis code combination (J80, J96.0, J96.2)

Clinician-documented diagnosis

Cohen’s kappa

0.85

0.61

0.63

0.70

Sensitivity, %

93 (86–97)

76 (67–84)

80 (81–88)

85 (77–91)

Specificity, %

92 (83–97)

87 (77–93)

84 (73–91)

85 (75–92)

Positive predictive value, %

94 (87–98)

89 (80–94)

87 (79–93)

89 (81–94)

Negative predictive value, %

91 (82–96)

73 (62–82)

76 (65–84)

81 (70–89)

  1. Diagnosis codes from International Classification of Diseases Tenth Revision (ICD-10). Reference standard was ascertained among 175 COVID-19 + patients