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Table 3 Spirometry parameters of Tet and control group before and after treatment

From: Tetrandrine slows the radiographic progression of progressive massive fibrosis in pneumoconiosis: a retrospective cohort study

 

Tet

Control

P-Value

FVC (ml)

Before administration

3222 ± 650

3272 ± 652

0.690

 

After administration

3301 ± 613

3185 ± 673

0.350

P -Value

 

0.021

0.00

 

Decline in FVC (ml) [M(P25, 75)]

-40(-250, 70)

85(47.5, 153.8)

0.000

FEV 1 (ml)

Before administration

2202 ± 492

2094 ± 742

0.690

 

After administration

2259 ± 514

1981 ± 747

0.030

P -Value

 

0.025

0.000

 

Decline in FEV 1 (ml) [M(P25, 75)]

-40.0(-170.0, 60.0)

120.0(25.0, 172.5)

0.000

FEV 1 /FVC

Before administration

69.33(63.68, 74.56)

64.57(54.13, 73.47)

0.450

 

After administration

68.93(63.28, 74.95)

61.05(51.56, 71.76)

0.003

P -Value

 

0.720

0.000

 

Decline in FEV 1 /FVC [M(P25,75)]

0.1(-1.39, 1.76)

1.75(-0.23, 3.45)

0.007

DLco%

Before administration

68.45 ± 14.11

70.88 ± 18.11

0.528

 

After administration

65.50 ± 11.17

68.72 ± 16.98

0.283

P -Value

 

0.000

0.003

 
  1. Twenty miners were missing spirometry parameters and were not included in the statistics presented. FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity. DLco: difusing capacity for carbon monoxide