Variables | Pulmonary cryptococcosis | Extrapulmonary cryptococcosis | P-value |
---|---|---|---|
Patients | 55 | 16 | N/A |
Gender | |||
Male | 27 (49.09%) | 11 (68.75%) | 0.165 |
Female | 28 (50.91%) | 5 (31.25%) | |
Age (mean ± SD) | 53.45 ± 12.47 | 54.75 ± 18.16 | |
Smoking e | 7 | 4 | 0.42 |
Exposure history a | 8 | 4 | 0.55 |
Preexisting immunocompromised conditions b | 13 (23.64%) | 12 (75%) | 0.000153 |
Diabetes mellitus | 4 | 4 | 0.127 |
Autoimmune disease | 5 | 6 | 0.018 |
Chronic renal disease | 2 | 3 | 0.127 |
Chronic hepatic diseases | 1 | 1 | |
Malignancies | 4 | 2 | 0.88 |
Long-term usage of immunosuppressants or glucocorticoids | 6 | 8 | 0.002 |
Immunosuppressants | 2 | 0 | |
Glucocorticoids | 3 | 1 | |
Immunosuppressants and glucocorticoids | 1 | 7 | |
HIV infection | 0 | 1 | |
Previous tuberculosis | 2 | 0 | |
History of organ transplantation | 0 | 0 | |
Hypertension | 17 | 4 | 0.89 |
Symptoms | 22 (40%) | 14 (87.5%) | 0.001 |
Fever | 5 | 11 | < 0.001 |
Headache | 0 | 8 | < 0.001 |
Respiratory symptomsc | 22 | 3 | 0.12 |
Laboratory tests | |||
Na+ (mmol/L) | 140.49 ± 2.64 | 137.77 ± 4.72 | 0.041ξ |
CRP > 5 mg/L | 29.4% (10/34) | 64.3% (9/14) | 0.025 |
CRP value (mg/L) | -- | -- | 0.012Ψ |
Monocyte counts (/uL) | 459.82 ± 167.28 | 363.12 ± 234.61 | 0.025Ψ |