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Fig. 3 | BMC Pulmonary Medicine

Fig. 3

From: Bioinformatics analysis of the immune cell infiltration characteristics and correlation with crucial diagnostic markers in pulmonary arterial hypertension

Fig. 3

Screening and functional enrichment analysis of DEGs. A The volcano plot shows DEGs between PAH and normal control. The blue dots represent downregulated DEGs, the red dots represent upregulated DEGs and the grey dots represent the genes that were not significantly changed. B The DEGs were visualized by the heatmap with red color for upregulation and blue color for downregulation. The enrichment analysis of DEGs includes GO functional analysis (C) and KEGG pathway enrichment (D); E GSEA plot showed that top five enriched KEGG pathways were positively correlated to PAH; F GSEA plot showed that TCA cycle was negatively correlated to PAH

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BMC Pulmonary Medicine

ISSN: 1471-2466

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