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Fig. 2 | BMC Pulmonary Medicine

Fig. 2

From: Tetramethylpyrazine ameliorates endotoxin-induced acute lung injury by relieving Golgi stress via the Nrf2/HO-1 signaling pathway

Fig. 2

TMP pretreatment alleviated apoptosis and oxidative stress in LPS-stimulated mice. A TUNEL staining for apoptosis in lung tissues. The number of TUNEL-positive cells was determined by a blinded pathologist (original magnification, × 400). Scale bar: 100 μm. B, C GSH and GSSG levels were detected using T-GSH/GSSG assay kit. D GSH/GSSG ratio. Data for the bar graphs are presented as mean ± SEM, and multiple comparisons were performed using one-way ANOVA with Bonferroni coefficient (n = 6). *Significant difference compared with the control group, *P < 0.05; #Significant difference compared with the LPS group, P < 0.05. ANOVA: analysis of variance; GSH: glutathione; GSSG: oxidized glutathione; LPS: lipopolysaccharide; SEM: standard error of the mean; TMP: tetramethylpyrazine

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BMC Pulmonary Medicine

ISSN: 1471-2466

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