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Table 3 The relationship between demographic and clinical variables and survival

From: Relationship between plasma circulating cell-free DNA concentration and treatment outcomes including prognosis in patients with advanced non-small cell lung cancer

Variables

Univariate

Multivariate

HR

95%CI

P value

HR

95%CI

P value

Gender (Female)

0.94

(0.61–1.45)

0.770

   

Age (≥ 65)

0.86

(0.58–1.28)

0.461

   

Smoking history (Yes)

0.99

(0.64–1.54)

0.974

   

ECOG PS (1–2)

1.07

(0.54–2.13)

0.837

   

Primary site (Right)

0.73

(0.49–1.07)

0.105

   

Histology(Squamous cell carcinoma and others)

1.55

(0.99–2.42)

0.056

   

Degree of differentiation (High)

1.19

(0.76–1.85)

0.456

   

Stage (IV)

0.70

(0.40–1.24)

0.225

   

Extrapulmonary metastasis (Yes)

1.50

(1.02–2.22)

0.042

1.68

(1.10–2.55)

0.016

Tumor size (≥ 5(cm))

1.57

(1.02–2.40)

0.041

1.43

(0.93–2.21)

0.100

BT1 cfDNA (≥ 15(ng/mL))

1.97

(1.29–3.01)

0.002

1.98

(1.26–3.11)

0.003

NLR (≥ 2.98)

1.57

(1.06–2.32)

0.024

1.86

(1.22–2.84)

0.004