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Table 4 Multivariate logistic regression analysis of risk factors for adverse outcomes combined with different diagnostic criteria

From: Comparison of two novel diagnostic criteria for bronchopulmonary dysplasia in predicting adverse outcomes of preterm infants: a retrospective cohort study

Variables

Joint 2018 NICHD definition

Joint 2019 Jensen definition

OR(95%CI)

P-value

OR(95%CI)

P-value

GA, w

 

0.511

 

0.722

 30 ≤ GA < 32

1.00

1.00

 28 ≤ GA < 30

0.703(0.386–1.278)

0.248

0.783(0.432–1.421)

0.421

 GA < 28

0.761(0.328–1.764)

0.524

0.859(0.371–1.993)

0.724

BW, g

 

0.326

 

0.384

 BW ≥ 1500

1.00

1.00

 1000 ≤ BW < 1500

1.439(0.722–2.868)

0.301

1.464(0.732–2.931)

0.281

 BW < 1000

2.117(0.793–5.651)

0.134

1.998(0.743–5.373)

0.170

EUGR at 36 weeks’ PMA

1.069(0.598–1.913)

0.821

1.013(0.565–1.817)

0.965

Treatment with PS

1.383(0.831–2.303)

0.212

1.414(0.850–2.351)

0.183

2018 BPD/2019 BPD

 

< 0.001

 

< 0.001

 No BPD

1.00

1.00

 Grade 1 BPD

3.745(1.712–8.189)

0.001

4.337(2.368–7.945)

< 0.001

 Grade 2 BPD

5.375(2.870−10.064)

< 0.001

14.569(6.732–31.527)

< 0.001

 Grade 3 BPD

23.961(11.359–50.541)

< 0.001

26.159(10.787–63.436)

< 0.001

  1. GA, gestational age; BW, birth weight; EUGR, extrauterine growth restriction; PMA, postmenstrual age; PS, pulmonary surfactant; BPD, bronchopulmonary dysplasia