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Table 2 Comparisons of echocardiographic findings, BNP, and WHO Fc between MCTD-PAH and MCTD-non-PAH patients

From: Association of red cell distribution width with pulmonary arterial hypertension in patients with mixed connective tissue disease

Variable

MCTD-PAH group

(n = 46)

MCTD-non-PAH group

(n = 73)

Statistical values

P

IVSTd [cm, M (P25-P75)]

0.8 (0.8–0.9)

0.8 (0.8–0.9)

-1.373

0.170

LVPWTd [cm, M (P25-P75)]

0.8 (0.8–0.9)

0.80 (0.8–0.9)

-0.969

0.333

LVEF [%, M (P25-P75)]

59.0 (58.0-60.3)

61.0 (60.0-61.5)

-2.970

0.003

LVDd (cm, \(\bar x\)±s)

4.5 ± 0.5

4.7 ± 0.4

-3.130

0.003

AoD [cm, M (P25-P75)]

2.8 (2.8–3.1)

3.0 (2.7–3.3)

-0.757

0.449

PA (m/s, \(\bar x\)±s)

0.8 ± 0.1

0.9 ± 0.2

-2.317

0.022

LVDs [cm, M (P25-P75)]

3.1 (2.8–3.3)

3.2 (3.0-3.3)

-1.737

0.082

LAD [cm, M (P25-P75)]

3.5 ± 0.7

4.4 ± 0.6

-2.079

0.038

E/A [M (P25-P75)]

0.9 (0.8–1.4)

1.2 (0.8–1.4)

-0.764

0.445

Pericardial effusion [P/N, n (%)]

17 (37.0)/29 (63.0)

15 (32.6)/58 (79.5)

3.865

0.049

PASP [mmHg, M (P25-P75)]

67.0 (48.5–90.0)

< 36

BNP [pg/mL, M (P25-P75)]

180.0 (63.8-478.5)

57.3 (22.8–112.0)

-5.621

< 0.001

WHO Fc

[I-II/III-IV, n (%)]

25 (54.4)/21 (45.7)

72 (98.6)/1 (1.4)

36.719

< 0.001

  1. IVSTd, interventricular septum thickness diastolic; LVPWTd, left ventricular posterior wall thickness at end-diastole; LVEF, left ventricle ejection fraction; LVDd, left ventricular diastolic dimension; AoD, aorta diameter; PA, pulmonary artery velocity; LVDs, left ventricular end-systolic dimension; LAD, left atrial diameter; E, mitral e peak; A, mitral a peak; PASP, pulmonary arterial systolic pressure; BNP, brain natriuretic peptide; WHO FC, World Health Organization functional class; P, positive; N, negative