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Table 3 Predictors of HFNC failure

From: Reliability of the respiratory rate and oxygenation index for successful high-flow nasal cannula support in coronavirus disease pneumonia: a retrospective cohort study

Variable

Risk ratio (95% CI)

P value

Age, ≥ 65 y

1.49 (1.02–2.16)

0.04

BMI, > 30 kg/m2

1.36 (0.84–2.20)

0.21

Smoking status

0.97 (0.66–1.42)

0.87

COPD

1.60 (0.93–2.77)

0.09

Malignancy

0.83 (0.43–1.62)

0.83

Cardiovascular disease

1.46 (0.90–2.37)

0.12

Cerebrovascular disease

1.27 (0.69–2.36)

0.44

Diabetes mellitus

1.31 (0.90–1.91)

0.15

Hypertension

0.69 (0.48–0.9989)

0.049

LDH level, > 450 U/L

1.72 (1.16–2.53)

0.006

CRP level, > 10 g/dL

1.05 (0.73–1.49)

0.81

ROX index, < 4.88

2.13 (1.47–3.06)

 < 0.001

  1. HFNC High-flow nasal cannula, BMI Body mass index, COPD Chronic obstructive pulmonary disease, LDH Lactate dehydrogenase, CRP C-reactive protein, ROX index Respiratory rate and oxygenation index, CI Confidence interval