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Table 1 Characteristics of included patients

From: Association between white blood cell count to hemoglobin ratio and risk of in-hospital mortality in patients with lung cancer

 

In-hospital mortality

 

Variables

Total (n = 768)

No (n = 615)

Yes (n = 153)

Statistics

P

WHR, n (%)

   

χ2 = 40.478

 < 0.001

  < 1.4

571 (74.35)

488 (79.35)

83 (54.25)

  

  >  = 1.4

197 (25.65)

127 (20.65)

70 (45.75)

  

PLR, n (%)

   

χ2 = 21.601

 < 0.001

  < 1.4

603 (78.52)

504 (81.95)

99 (64.71)

  

  >  = 1.4

165 (21.48)

111 (18.05)

54 (35.29)

  

Age, year, Mean ± SD

68.17 ± 10.39

68.03 ± 10.31

68.75 ± 10.73

t = -0.76

0.446

Race, n (%)

   

χ2 = 0.051

0.822

 White

648 (84.38)

518 (84.23)

130 (84.97)

  

 Other

120 (15.63)

97 (15.77)

23 (15.03)

  

BMI, kg/m2, Mean ± SD

26.01 ± 6.43

26.03 ± 6.34

25.92 ± 6.79

t = 0.19

0.852

Heart rate, times/minute, Mean ± SD

99.60 ± 23.46

97.69 ± 23.04

107.25 ± 23.62

t = -4.57

 < 0.001

Respiratory rate, breaths/minute, Mean ± SD

21.56 ± 6.43

21.34 ± 6.32

22.43 ± 6.81

t = -1.88

0.061

SBP, mmHg, Mean ± SD

121.76 ± 28.10

123.01 ± 28.47

116.73 ± 26.09

t = 2.48

0.013

DBP, mmHg, Mean ± SD

68.89 ± 17.18

69.56 ± 16.86

66.21 ± 18.23

t = 2.17

0.031

Temperature, °C, Mean ± SD

36.79 ± 0.74

36.79 ± 0.69

36.76 ± 0.92

t = 0.32

0.747

Creatinine, mg/dL, M (Q1, Q3)

0.90 (0.69, 1.30)

0.89 (0.69, 1.23)

1.03 (0.70, 1.52)

Z = 2.482

0.013

BUN, mg/dL, M (Q1, Q3)

19.00 (13.00, 29.00)

18.00 (13.00, 26.00)

25.00 (17.00, 38.00)

Z = 5.553

 < 0.001

Glucose, mg/dl, M (Q1, Q3)

133.00 (106.00, 168.00)

132.00 (106.00, 161.00)

138.00 (107.00, 180.00)

Z = 1.344

0.179

Bicarbonate, mmol/L, Mean ± SD

25.41 ± 5.27

25.47 ± 5.08

25.17 ± 5.99

t = 0.56

0.574

Sodium, mmol/L, Mean ± SD

136.16 ± 5.89

136.24 ± 5.85

135.85 ± 6.05

t = 0.73

0.467

Potassium, mmol/L, Mean ± SD

4.19 ± 0.71

4.16 ± 0.68

4.33 ± 0.79

t = -2.46

0.015

Chloride, mmol/L, Mean ± SD

100.91 ± 6.88

101.12 ± 6.99

100.05 ± 6.35

t = 1.72

0.086

CAD, n (%)

   

χ2 = 2.163

0.141

 No

491 (63.93)

401 (65.20)

90 (58.82)

  

 Yes

277 (36.07)

214 (34.80)

63 (41.18)

  

CHF, n (%)

   

χ2 = 0.000

0.985

 No

683 (88.93)

547 (88.94)

136 (88.89)

  

 Yes

85 (11.07)

68 (11.06)

17 (11.11)

  

AF, n (%)

   

χ2 = 3.810

0.051

 No

638 (83.07)

519 (84.39)

119 (77.78)

  

 Yes

130 (16.93)

96 (15.61)

34 (22.22)

  

RF, n (%)

   

χ2 = 15.271

 < 0.001

 No

666 (86.72)

548 (89.11)

118 (77.12)

  

 Yes

102 (13.28)

67 (10.89)

35 (22.88)

  

Diabetes, n (%)

   

χ2 = 0.111

0.739

 No

659 (85.81)

529 (86.02)

130 (84.97)

  

 Yes

109 (14.19)

86 (13.98)

23 (15.03)

  

Hypertension, n (%)

   

χ2 = 0.743

0.389

 No

608 (79.17)

483 (78.54)

125 (81.70)

  

 Yes

160 (20.83)

132 (21.46)

28 (18.30)

  

Chronic kidney disease, n (%)

   

χ2 = 0.025

0.876

 No

731 (95.18)

585 (95.12)

146 (95.42)

  

 Yes

37 (4.82)

30 (4.88)

7 (4.58)

  

Ventilation, n (%)

   

χ2 = 36.636

 < 0.001

 No

585 (76.17)

497 (80.81)

88 (57.52)

  

 Yes

183 (23.83)

118 (19.19)

65 (42.48)

  

RRT, n (%)

   

-

0.768

 No

750 (97.66)

601 (97.72)

149 (97.39)

  

 Yes

18 (2.34)

14 (2.28)

4 (2.61)

  

Vasopressor, n (%)

   

χ2 = 32.960

 < 0.001

 No

637 (82.94)

534 (86.83)

103 (67.32)

  

 Yes

131 (17.06)

81 (13.17)

50 (32.68)

  

APACHE score, M (Q1,Q3)

58.00 (46.00, 75.00)

55.00 (44.00, 70.00)

74.00 (58.00, 88.00)

Z = 7.884

 < 0.001

Sedative, n (%)

   

χ2 = 3.180

0.075

 No

732 (95.31)

582 (94.63)

150 (98.04)

  

 Yes

36 (4.69)

33 (5.37)

3 (1.96)

  

Opioid, n (%)

   

χ2 = 2.163

0.141

 No

491 (63.93)

401 (65.20)

90 (58.82)

  

 Yes

277 (36.07)

214 (34.80)

63 (41.18)

  

Tumor type, n (%)

   

χ2 = 3.605

0.307

 Primary lung cancer

570 (74.22)

462 (75.12)

108 (70.59)

  

 Denocarcinoma

68 (8.85)

50 (8.13)

18 (11.76)

  

 Squamous cell carcinoma

61 (7.94)

51 (8.29)

10 (6.54)

  

 Others

69 (8.98)

52 (8.46)

17 (11.11)

  

ICU stay time, min, M (Q1, Q3)

4111.00 (2517.50, 7089.00)

3867.00 (2434.00, 6835.00)

5309.00 (3182.00, 8956.00)

Z = 4.205

 < 0.001

  1. WHR white blood cells/hemoglobin, PLR platelet count/lymphocytes count, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, BUN blood urea nitrogen, CAD coronary artery disease, CHF congestive heart failure, AF Atrial fibrillation, RF Renal failure, RRT rapid resolution therapy, APACHE Acute Physiology and Chronic Health Evaluation, ICU intensive care unit
  2. t: t test; Z: rank sum test; χ2: chi-square test; -: Fisher exact probability; Mean ± SD: means +—standard deviation; M: Median; Q1: 1st Quartile; Q3: 3st Quartile