A systematic review of the clinical impact of small colony variants in patients with cystic fibrosis

Ryan, Harrigan; Ballard, Emma; Stockwell, Rebecca E.; Duplancic, Christine; Thomson, Rachel M.; Smith, Kimberley; Bell, Scott C.

doi:10.1186/s12890-023-02611-4

BMC Pulmonary Medicine

Table 1 Included studies in the systematic review

From: A systematic review of the clinical impact of small colony variants in patients with cystic fibrosis

Papers		Study Methodology				Clinical and Microbiological Data
Study	Country	Study Design	Cohort	Total Participants	Bacterial Pathogen	SCV Prevalence	SCV Diagnosis	AST of SCVs	Lung Function Parameters	Risk factors for SCVs
Anderson et al. [29]	USA	Cross-sectional	NA	NA	S. maltophilia	✓	✓	✓
Besier et al. [11]	Germany	Prospective cohort	Adult and Paediatric	252	S. aureus	✓	✓	✓	✓	✓
Besier et al. [30]	Germany	Cross-sectional	NA	NA	S. aureus	✓	✓	✓
Carzino et al. [31]	Australia	Prospective cohort	Paediatric	41	S. aureus	✓	✓
De Souza et al. [32]	Brazil	Case series	Paediatric	1	S. aureus		✓	✓
Dodement et al. [33]	Belgium	Prospective cohort	Adult and Paediatric	510	S. aureus	✓	✓	✓		✓
Haussler et al. [26]	Germany	Prospective cohort	Adult and Paediatric	346	P. aeruginosa	✓	✓	✓	✓
Haussler et al. [34]	Germany	Prospective cohort	Adult and Paediatric	470	Bcc	✓	✓		✓
Junge et al. [35]	Germany	Prospective cohort	Adult and Paediatric	195	S. aureus	✓	✓		✓	✓
Kahl et al. [36]	Germany	Prospective cohort	Adult and Paediatric	78	S. aureus	✓	✓	✓		✓
Kahl et al. [37]	Germany	Prospective cohort	Adult and Paediatric	72	S. aureus	✓
Lozano et al. [38]	Spain	Case series	NA	NA	P. aeruginosa			✓
Masoud-Landgraf et al. [25]	Austria	Cross-sectional	Adult and Paediatric	147	S. aureus	✓	✓	✓
Moisan et al. [19]	Canada	Cross-sectional	NA	17	S. aureus	✓	✓	✓
Morelli et al. [16]	Italy	Cross-sectional	Adult and Paediatric	222	S. aureus	✓	✓	✓		✓
Pakasticali et al. [39]	Turkey	Cross-sectional	Adult and Paediatric	84	S. aureus	✓	✓	✓		✓
Precit et al. [40]	USA	Cross-sectional	Paediatric	23	S. aureus		✓	✓
Schneider et al. [24]	Switzerland	Cross-sectional	Adult and Paediatric	98	S. aureus and P. aeruginosa	✓	✓		✓	✓
Schwerdt et al. [41]	Germany	Retrospective cohort	Adult and Paediatric	283	S. aureus	✓			✓
Suwantarat et al. [42]	USA	Cross-sectional	Adult and Paediatric	NA	S. aureus	✓	✓	✓	✓	✓
Tkadlec et al. [43]	Czech Republic	Cross-sectional	Adult and Paediatric	107	S. aureus	✓	✓	✓		✓
Vergison et al. [44]	Belgium	Prospective cohort	Adult and Paediatric	594	S. aureus	✓	✓	✓		✓
Wolter et al. [23]	USA	Prospective cohort	Paediatric	100	S. aureus	✓	✓		✓	✓
Wolter et al. [14]	USA	Prospective cohort	Paediatric	230	S. aureus	✓	✓		✓	✓
Yagci et al. [12]	Turkey	Prospective cohort	Adult and Paediatric	248	S. aureus	✓	✓	✓		✓

SCV small colony variant, S. aureus Staphylococcus aureus, P. aeruginosa Pseudomonas aeruginosa, Bcc Burkholderia cepacia complex, AST Antimicrobial susceptibility testing

Back to article page

ISSN: 1471-2466

Contact us

Submission enquiries: bmcpulmonarymedicine@biomedcentral.com
General enquiries: ORSupport@springernature.com