| Univariate | Multivariate model 1 | Multivariate model 2 | ||||||
---|---|---|---|---|---|---|---|---|---|
 | HR | 95% CI | p-value | HR | 95% CI | p-value | HR | 95% CI | p-value |
Age > 65 years | 20.31 | 2.36–174.7 | 0.006 | 44.04 | 2.65–732.1 | 0.008 | 13.41 | 1.47–121.8 | 0.021 |
Anti-CCP | 1.002 | 0.99–1.01 | 0.124 |  |  |  |  |  |  |
CRP | 6.172 | 0.32–118.5 | 0.227 |  |  |  |  |  |  |
R5 > 150% | 1.031 | 1.01–1.06 | 0.013 |  |  |  |  |  |  |
R20 > 150% | 1.023 | 0.99–1.05 | 0.083 |  |  |  |  |  |  |
R5-R20 > 0.07 | 2.671 | 0.69–10.33 | 0.154 | 0.126 | 0.008–1.87 | 0.132 |  |  |  |
AX > 0.44 | 7.466 | 1.79–30.99 | 0.006 | 3.348 | 0.267–41.98 | 0.349 |  |  |  |
Fres > 14.14 | 9.629 | 2.33–43.01 | 0.003 | 18.01 | 1.15–282.7 | 0.039 |  |  |  |
X5 < -0.12 | 1.450 | 0.30–6.91 | 0.641 |  |  |  |  |  |  |
FVC < 80% | 539E + 006 | - | 0.997 |  |  |  |  |  |  |
FEV1/FVC < 70% | 2.001 | 0.211–18.95 | 0.545 |  |  |  |  |  |  |
MMEF < 65% | 8.250 | 1.58–43.02 | 0.012 |  |  |  | 4.421 | 0.736–26.53 | 0.104 |
DLCO < 76% | 1.385 | 0.381–5.034 | 0.621 |  |  |  |  |  |  |