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Table 4 Univariate and multivariate analyses of spirometry and IOS parameters associated with patients with rheumatoid arthritis with abnormal findings in HRCT

From: Application of impulse oscillometry to detect interstitial lung disease and airway disease in adults with rheumatoid arthritis

 

Univariate

Multivariate model 1

Multivariate model 2

 

HR

95% CI

p-value

HR

95% CI

p-value

HR

95% CI

p-value

Age > 65 years

20.31

2.36–174.7

0.006

44.04

2.65–732.1

0.008

13.41

1.47–121.8

0.021

Anti-CCP

1.002

0.99–1.01

0.124

      

CRP

6.172

0.32–118.5

0.227

      

R5 > 150%

1.031

1.01–1.06

0.013

      

R20 > 150%

1.023

0.99–1.05

0.083

      

R5-R20 > 0.07

2.671

0.69–10.33

0.154

0.126

0.008–1.87

0.132

   

AX > 0.44

7.466

1.79–30.99

0.006

3.348

0.267–41.98

0.349

   

Fres > 14.14

9.629

2.33–43.01

0.003

18.01

1.15–282.7

0.039

   

X5 < -0.12

1.450

0.30–6.91

0.641

      

FVC < 80%

539E + 006

-

0.997

      

FEV1/FVC < 70%

2.001

0.211–18.95

0.545

      

MMEF < 65%

8.250

1.58–43.02

0.012

   

4.421

0.736–26.53

0.104

DLCO < 76%

1.385

0.381–5.034

0.621

      
  1. CCP Cyclic citrullinated peptide antibody, C-reactive protein, DLCO Diffusing capacity of the lung for carbon monoxide, FVC Forced vital capacity, FEV1 Forced expiratory volume in one second, HRCT High-resolution computed tomography, IOS Impulse oscillometry, MMEF Maximal mid expiratory flow curve