Table 2 Diagnosis performance of enrolled literature in the meta-analysis
Study | lncRNA | TP | FP | FN | TN | SEN% | SPE% | AUC |
|---|---|---|---|---|---|---|---|---|
COPD vs. NC | ||||||||
Ge2019 [25] | ANRIL | 96 | 84 | 42 | 56 | 69.6% | 40.0% | 0.543 |
Ming2019 [13] | NEAT1 | 70 | 46 | 20 | 44 | 77.8% | 48.9% | 0.642 |
Du2020 [27] | PACER | 37 | 1 | 18 | 44 | 66.7% | 97.8% | 0.867 |
Wang2020a [28] | LINC00987 | 22 | 3 | 7 | 30 | 76.2% | 91.2% | 0.798 |
Wang2020b [29] | PVT1 | 62 | 21 | 18 | 59 | 77.6% | 73.9% | 0.813 |
Hao2021 [31] | OIP5-AS1 | 54 | 10 | 8 | 45 | 87.1% | 81.4% | 0.903 |
Liu2021 [32] | CASC2 | 39 | 4 | 11 | 46 | 78.0% | 92.0% | 0.924 |
Zhao2021 [33] | LUCAT1 | 67 | 40 | 3 | 30 | 95.5% | 42.4% | 0.892 |
Mao2022 [35] | PVT1 | 269 | 7 | 31 | 58 | 89.6% | 89.7% | 0.878 |
Wei2022 [36] | MEG3 | 33 | 10 | 10 | 16 | 76.9% | 60.0% | 0.661 |
Xu2022 [37] | LINC00599 | 23 | 2 | 7 | 28 | 76.7% | 93.3% | 0.896 |
Xiao2023 [38] | LINC00612 | 24 | 2 | 8 | 32 | 75.0% | 93.9% | 0.929 |
AECOPD vs. NC | ||||||||
Ge2019 [25] | ANRIL | 122 | 70 | 14 | 70 | 89.7% | 50.0% | 0.700 |
Ming2019 [13] | NEAT1 | 84 | 28 | 6 | 62 | 93.3% | 68.9% | 0.869 |
Qi2019†[26] | NR-026690 | 55 | 19 | 1 | 16 | 98.2% | 46.4% | 0.757 |
Qi2019†[26] | ENST00000447867 | 47 | 11 | 9 | 24 | 83.3% | 68.2% | 0.721 |
Liu2020 [14] | MALAT1 | 119 | 20 | 1 | 100 | 99.2% | 83.3% | 0.969 |
Wang2020b [29] | PVT1 | 67 | 5 | 13 | 75 | 83.6% | 93.8% | 0.953 |
AECOPD vs. COPD | ||||||||
Ge2019 [25] | ANRIL | 122 | 77 | 14 | 61 | 89.7% | 44.2% | 0.659 |
Ming2019 [13] | NEAT1 | 79 | 28 | 11 | 56 | 87.8% | 62.2% | 0.779 |
Qi2019†[26] | NR-026690 | 33 | 7 | 18 | 44 | 64.3% | 86.0% | 0.838 |
Qi2019†[26] | ENST00000447867 | 19 | 5 | 32 | 46 | 38.1% | 89.3% | 0.666 |
Liu2020 [14] | MALAT1 | 77 | 20 | 43 | 100 | 64.2% | 83.3% | 0.846 |
Wang2020b [29] | PVT1 | 40 | 8 | 40 | 72 | 50.0% | 90.0% | 0.739 |
Wu2020 [30] | Lnc-IL7R | 17 | 8 | 2 | 19 | 89.5% | 70.4% | 0.856 |
Chen2021 [15] | NEAT1 | 103 | 15 | 19 | 163 | 84.4% | 91.6% | 0.887 |
Bamodu2022 [34] | Lnc-IL7R | 88 | 3 | 19 | 15 | 83.0% | 83.3% | 0.858 |