Table 3 Risk of hypercapnic respiratory failure by potential underlying cause
From: Causes of hypercapnic respiratory failure: a population-based case-control study
Odds Ratio (95% CI) | Population attributable fractiona (95% CI) | ||
|---|---|---|---|
Cause | Unadjusted | Adjusted | |
Chronic obstructive pulmonary disease | 7.49 (3.16 – 17.8) | 5.30 (1.95 – 14.4) | 42% (18% – 59%) |
Congestive cardiac failure | 21.7 (2.80 – 166) | 13.4 (1.40 – 128) | 24% (7% – 38%) |
Moderate-to-severe obstructive sleep apnea | 1.14 (0.46 – 2.81) | 0.38 (0.10 – 1.53) | NA |
Respiratory muscle weakness | 5.11 (2.11 – 12.3) | 5.11 (2.11 – 12.3) | 31% (11% – 46%) |
Opioid use | 3.85 (1.82 – 8.17) | 3.64 (1.49 – 8.88) | 41% (13% – 59%) |
Benzodiazepine use | 1.30 (0.48 – 3.49) | 1.30 (0.48 – 3.49) | NA |