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Table 2 Sensitivity, specificity, Youden index, PLR, NLR, PPV, and NPV of pleural fluid ADA to serum CRP ratio and pleural fluid ADA in diagnosing patients with tuberculous pleural effusion

From: Pleural fluid adenosine deaminase to serum C-reactive protein ratio for diagnosing tuberculous pleural effusion

ย 

Cut-off

Sensitivity (%)

Specificity (%)

Youden index (%)

PPV (%)

NPV (%)

PLR

NLR

ADA/CRP

1.25

93.8

85.2

78.9

88.2

92

6.33

0.07

ADA (U/L)

40.3

81.3

88.9

70.1

89.7

80.0

7.31

0.21

  1. PLR positive likelihood ratio, PPV positive predictive value, NLR negative likelihood ratio, NPV negative predictive value
  2. Youden Index, Jโ€‰=โ€‰max (sensitivityโ€‰+โ€‰specificity-1)