Table 1 Demographic characteristics of total study population

Demographics

 Age

58 [48, 70]

60 [47, 70]

65 [57, 73]

53 [42.5, 60]

 < 0.001

 < 0.001

 < 0.001

 Male sex

848 (61.8%)

646 (67.2%)

74 (44.3%)

41 (43.2%)

 < 0.001

 < 0.001

0.959

 Body mass index, kg/m²

21.5 [19.3, 23.6]

21.5 [19.4, 23.8]

20.0 [18.6, 22.3]

23.0 [20.4, 24.8]

 < 0.001

 < 0.001

 < 0.001

Comorbidity

 Previous TB history

213 (15.8%)

149 (15.6%)

42 (25.9%)

0 (0.0%)

0.002

 < 0.001

 < 0.001

 Diabetes

173 (21.7%)

147 (26.0%)

8 (6.6%)

5 (11.4%)

 < 0.001

0.047

0.500

 COPD

23 (2.9%)

12 (2.1%)

7 (5.8%)

1 (2.3%)

0.055

 > 0.999

0.604

 Hypertension

155 (19.4%)

110 (19.5%)

26 (21.1%)

6 (13.6%)

0.704

0.453

0.365

Laboratory findings

 WBC, /μL×1000

6.2 [5.0, 7.9]

6.4 [5.1, 8.1]

6.1 [5.0, 7.6]

5.7 [4.7, 6.9]

0.185

0.003

0.098

 Neutrophil, %

62.0 [53.7, 69.8]

62.5 [53.9, 70.5]

61.7 [54.3, 69.0]

56.7 [51.2, 62.9]

0.535

 < 0.001

0.005

 Lymphocyte, %

25.7 ± 10.7

25.1 ± 11.0

26.7 ± 10.1

31.3 ± 8.1

0.098

 < 0.001

0.001

 Hb, g/dL

13.1 ± 1.8

13.0 ± 1.9

12.9 ± 1.6

14.0 ± 1.4

0.732

 < 0.001

 < 0.001

 Platelet, /μL×1000

265.8 ± 97.6

268.8 ± 98.7

252.2 ± 97.3

232.2 ± 57.1

0.049

 < 0.001

0.041

 Albumin, g/dL

4.2 [3.8, 4.4]

4.1 [3.7, 4.4]

4.2 [3.9, 4.4]

4.4 [4.2, 4.5]

0.035

 < 0.001

 < 0.001

 Protein, g/dL

7.2 [6.8, 7.6]

7.2 [6.8, 7.7]

7.3 [6.95, 7.7]

7.2 [7.0, 7.45]

 < 0.001

0.100

0.047

Radiographic feature

 Cavity

114 (8.3%)

84 (8.7%)

20 (12.0%)

0 (0.0%)

0.229

0.005

0.001