Table II The transition of marker levels and percentage remaining above cut-off levels in the next test in subjects with elevated marker levels in one test

CYFEA 21 − 1

 Median [IQR] (ng/ml)

  At the baseline

4.0 [3.8, 4.5]

4.2 [3.9, 4.5]

4.4 [4.0, 4.7]

4.2 [3.8, 4.8]

  In the next test

3.0 [2.3, 4.0]

3.3 [2.5, 4.0]

3.1 [2.4, 3.8]

2.9 [2.4, 3.8]

 Number (%) (> 3.5 ng/ml)

  At the baseline

33

43

52

54

  In the next test

12 (36%)

16 (37%)

19 (37%)

15 (28%)

CEA

 Median [IQR] (ng/ml)

  At the baseline

9.0 [5.5, 9.3]

6.0 [5.6, 7.8]

6.4 [5.4, 7.7]

5.7 [5.5, 8.1]

  In the next test

7.1 [4.7, 10]

5.5 [4.9, 7.2]

6.9 [5.7, 8.2]

6.4 [4.7, 7.5]

 Number (%) (> 5.0 ng/ml)

  At the baseline

5

8

6

7

  In the next test

3 (60%)

6 (75%)

5 (83%)

5 (71%)