Table III Characteristics of subjects in the final test
Total | Not frequently elevated | Frequently elevated | p-value | ||
|---|---|---|---|---|---|
Number of subjects | 951 | 892 | 59 | ||
Sex (male, %) | 77.5 | 77.5 | 78.0 | 1.000 | |
Age at the baseline | |||||
Median [IQR] (years) | 54 [47, 61] | 54 [47, 60] | 61 [55, 67] | < 0.001 | |
Categories (%) | < 50 | 31.4 | 32.5 | 15.2 | < 0.001 |
50–64 | 54.4 | 54.9 | 45.8 | ||
≥ 65 | 14.2 | 12.6 | 39.0 | ||
BMI at the baseline | |||||
Median [IQR] | 23.1 [21.3, 25.2] | 23.2 [21.4, 25.2] | 22.0 [20.8, 25.1] | 0.111 | |
Categories (%) | < 25 | 73.2 | 73.2 | 72.9 | 1.000 |
≥ 25 | 26.8 | 26.8 | 27.1 | ||
Weight change in the follow-up period | |||||
Maintenance or gain | 58.1 | 59.2 | 42.4 | 0.016 | |
Loss | 41.9 | 40.8 | 57.6 | ||
Smoking status at the baseline | |||||
Categories (%) | Non-smoker | 39.6 | 40.2 | 30.5 | 0.057 |
Ex-smoker | 40.7 | 40.8 | 39.0 | ||
Current (pack-year < 20) | 7.1 | 7.1 | 6.8 | ||
Current (pack-year ≥ 20) | 12.6 | 11.9 | 23.7 | ||
Number of times (CYFRA 21 − 1 > 3.5 ng/ml) | |||||
the rate of numbers (%) | 0 | 84.9 | 90.5 | 0 | < 0.001 |
1 | 8.9 | 9.5 | 0 | ||
2 | 3.7 | 0 | 59.3 | ||
3 | 1.9 | 0 | 30.5 | ||
4 | 0.4 | 0 | 6.8 | ||
5 | 0.2 | 0 | 3.4 | ||
Number of times (CEA > 5.0 ng/ml) | |||||
the rate of numbers (%) | 0 | 98.8 | 98.9 | 96.6 | 0.198 |
1 | 0.6 | 0.6 | 1.7 | ||
2 | 0.1 | 0.1 | 0 | ||
3 | 0 | 0 | 0 | ||
4 | 0.2 | 0.2 | 0 | ||
5 | 0.3 | 0.2 | 1.7 | ||