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Table 1 Baseline characteristics of ARDS patients in MIMIC-III

From: Machine learning-based prediction model of acute kidney injury in patients with acute respiratory distress syndrome

 

Non-AKI

(N = 749)

AKI

(N = 179)

P-value

Gender

  

0.315

Male

448 (59.8%)

115 (64.2%)

 

Female

301 (40.2%)

64 (35.8%)

 

Age

  

0.259

Under 50

187 (25.0%)

38 (21.2%)

 

Between 50–70

355 (47.4%)

97 (54.2%)

 

Above 70

207 (27.6%)

44 (24.6%)

 

ARDS

  

0.012

Mild-ARDS

117 (15.6%)

25 (14.0%)

 

Severe-ARDS

291 (38.9%)

91 (50.8%)

 

Moderate-ARDS

341 (45.5%)

63 (35.2%)

 

BMI*

28.4 [9.86, 115]

28.3 [10.8, 91.6]

0.907

BE*

1.00 [-33.0, 16.0]

-1.00 [-34.0, 12.0]

< 0.001

BUN*

16.0 [3.00, 76.0]

28.0 [7.00, 114]

< 0.001

Calcium

8.40 (0.926)

8.17 (0.965)

0.00386

Chloride

105 (6.05)

104 (7.04)

0.0823

Creatinine*

0.800 [0.200, 2.50]

1.30 [0.300, 3.80]

< 0.001

DBP

65.0 (14.9)

63.3 (15.7)

0.19

Glucose*

121 [39.0, 508]

126 [40.0, 560]

0.0668

HCO3

25.7 (4.34)

24.0 (5.32)

< 0.001

Hematocrit

32.7 (6.22)

32.5 (6.95)

0.688

Hemoglobin

11.0 (2.15)

10.8 (2.32)

0.23

HR

87.3 (16.8)

95.1 (19.0)

< 0.001

Potassium

4.10 (0.567)

4.22 (0.684)

0.0324

Lactate*

1.50 [0.400, 13.5]

2.20 [0.700, 12.7]

< 0.001

MAP

82.3 (15.7)

78.5 (16.9)

0.00554

Sodium

139 (4.48)

139 (6.59)

0.705

PCO2*

42.0 [16.0, 119]

42.0 [19.0, 96.0]

0.327

PH

7.38 (0.0969)

7.34 (0.124)

< 0.001

Phosphate*

3.30 [1.20, 9.20]

3.70 [1.30, 12.4]

< 0.001

Platelets*

212 [5.00, 871]

214 [16.0, 796]

0.228

PO2*

233 [24.0, 567]

107 [24.0, 607]

< 0.001

RBC

3.69 (0.741)

3.59 (0.813)

0.144

RR*

0 [0, 45.0]

0 [0, 43.0]

0.245

SBP

121 (23.2)

118 (24.9)

0.234

SpO2

98.1 (4.24)

96.5 (4.01)

< 0.001

Temperature*

36.8 (0.852)

36.9 (1.15)

0.22

WBC*

10.6 [0.300, 46.8]

11.7 [0.400, 50.7]

0.00905

UO*

1650 [20.0, 6090]

1180 [30.0, 5980]

0.00153

Albumin

3.41 (0.712)

2.98 (0.759)

< 0.001

ALT*

25.0 [3.00, 1770]

32.0 [6.00, 2550]

0.00879

AST*

31.0 [7.00, 1900]

51.0 [10.0, 5570]

0.00404

TBIL*

0.500 [0.100, 37.5]

0.800 [0.100, 52.6]

< 0.001

RDW

14.4 (1.68)

15.7 (2.40)

< 0.001

INR*

1.20 [0.900, 4.10]

1.30 [0.900, 4.80]

< 0.001

PTT*

28.6 [17.0, 150]

31.1 [18.1, 150]

< 0.001

PT*

13.6 [10.0, 40.1]

14.5 [10.3, 49.9]

< 0.001

PEEP*

5.00 [0, 24.0]

5.00 [0, 24.0]

< 0.001

Diabetes

  

0.00337

Non-DM

583 (77.8%)

120 (67.0%)

 

DM

166 (22.2%)

59 (33.0%)

 

UTI

  

0.00105

Non-UTI

681 (90.9%)

147 (82.1%)

 

UTI

68 (9.1%)

32 (17.9%)

 

Sepsis

  

< 0.001

Non-Sepsis

699 (93.3%)

101 (56.4%)

 

Sepsis

50 (6.7%)

78 (43.6%)

 
  1. * Wilcoxon rank-sum test
  2. ARDS, acute respiratory distress syndrome; MIMIC, Medical Information Mort for Intensive Care; AKI, acute kidney injury; UTI, urinary tract infection; BMI, body mass index; BE, base excess; BUN, blood urea nitrogen; DBP, diastolic blood pressure; ABC, actual bicarbonate radical; HR, heart rate; MAP, mean arterial pressure; PCO2, partial pressure of carbon dioxide; PO2, partial arterial oxygen pressure; RBC, red blood cell; RR, respiratory rate; SBP, systolic blood pressure; SpO2, oxygen saturation; WBC, white blood cell; UO, urine output; ALT, alanine aminotransferase; AST, aspartate aminotransferase; TBIL, total bilirubin; RDW, red cell volume distribution width; INR, international normalized ratio; PTT, partial thromboplastin time; PT, prothrombin time; PEEP, positive end expiratory pressure
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BMC Pulmonary Medicine

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