Fig. 1

The expression of PEDF decreased during LPS-induced ALI in rats. A H&E-stained cross-section of the lung from LPS-exposed rats at the corresponding point in time. Scale bars: 200 μm. B The pathological scores of the Normal group and LPS (1d, 2d, 4d) group. n = 5. C Quantitative analysis of lung W/D ratio. Quantification of cytokines. D TNF-α, E IL-6, and F IL-1β expression levels. G Quantitative analysis of lung tissue MPO activity and H the number of neutrophils. I PEDF mRNA expression of lung tissue and J content of BALF. n = 5, Data are expressed as the mean ± SD, *P < 0.05; **P < 0.01; ***P < 0.001 vs. Normal group