Fig. 7

PEDF reduced LPS-induced inflammatory in RLE-6TN cells by upregulating PPAR-γ. A Immunoblot analysis of NLRP3, p38 MAPK, phospho-p38 MAPK, NF-κB p65, phospho-NF-κB p65. B, C and D Quantification of the related protein expression. Quantification of TNF-α (E), IL-6 (F), and IL-1β (G) concentrations in the cell supernatant. Data are expressed as the mean ± SD, n = 4, *P < 0.05; **P < 0.01 vs. indicated group