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Table 1 Clinical characteristics in non-survival and survival groups

From: Receiver operating characteristic (ROC) to determine cut-off points of clinical and biomolecular markers to discriminate mortality in severe COVID-19 living at high altitude

Characteristics

Total

Condition at discharge

p-value

No-survival

Survival

Age (mean (SD)) years1/

51,73 (12,40)

58,07 (11,02)

48,37 (11,8)

0,000*

Gender (n (%))2/

 Male

146 (71,22)

56 (38,36)

90 (61,64)

0,078

 Female

59 (28,78)

15 (25,42)

44 (74,58)

T2DM (%))2/

 Yes

28 (13,66)

11 (39,29)

17 (60,71)

0,578

 No

177 (86,34)

60 (33,9)

117 (66,1)

HBP (n (%))2/

 Yes

34 (16,59)

15 (44,12)

19 (55,88)

0,203

 No

171 (83,41)

56 (32,75)

115 (67,25)

Obesity (n (%))2/

 Yes

54 (26,34)

15 (27,78)

39 (72,22)

0,217

 No

151 (73,66)

56 (37,09)

95 (62,91)

 BMI (mean (SD))3/

29,66 (4,54)

29,04 (4,78)

30,01 (4,38)

0,060

 APACHE II at admission (mean (SD))3/

17,24 (6,04)

18,79 (6,47)

16,42 (5,66)

0,010*

SOFA (mean (SD))3/

 24 h

7,55 (2,93)

8,45 (3,33)

7,07 (2,57)

0,006*

 48 h

5,93 (2,65)

6,83 (2,87)

5,48 (2,42)

0,002*

 72 h

5,18 (2,71)

6,47 (2,9)

4,56 (2,39)

0,000*

 Corticosteroids use (n (%))2/

183 (89,27)

63 (34,43)

120 (65,57)

0,857

 Heparin use (n (%))2/

161 (78,92)

59 (36,65)

102 (63,35)

0,175

 Hospitalization days (mean (SD))3/

10,27 (7,33)

10,55 (7,34)

10,13 (7,35)

0,556

  1. T2DM Type 2 diabetes mellitus, HBP High blood pressure, BMI Body mass index, APACHE Acute Physiology and Chronic Health Evaluation II Score, SOFA Sequential Organ Failure Assessment Score, SD Standard Deviation; *significant differences (p-value < 0.05). 1/ T-test 3/ Mann Whitney U test; 2/ comparison with no-survival condition based on Chi-square test or exact Fisher test; OR Odds Ratio, CI Confidence interval