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Table 2 Biomarkers characteristic in non-survival and survival groups

From: Receiver operating characteristic (ROC) to determine cut-off points of clinical and biomolecular markers to discriminate mortality in severe COVID-19 living at high altitude

Biomarker

Total

Condition at discharge

p-value

No-survival

Survival

D-dimer 24 h(mean (SD)) ng/ml2/

2651,37 (5111,96)

3449,75 (7995,3)

2224,76 (2397,36)

0,202

D-dimer 48 h(mean (SD)) ng/ml2/

2667,57 (2880,31)

3647,66 (3629,45)

2165,86 (2275,08)

0,063

D-dimer 72 h(mean (SD)) ng/ml2/

2649,47 (2340,94)

3392,09 (2913,78)

2252,25 (1889,5)

0,189

Ferritin 24 h (mean (SD)) ng/ml2/

1117,68 (489,78)

1233,61 (435,71)

1055,79 (507,1)

0,049*

Ferritin 48 h (mean (SD)) ng/ml2/

1109,64 (464,48)

1181,81 (400,23)

1076,92 (489,54)

0,323

Ferritin 72 h (mean (SD)) ng/ml2/

1236,65 (777,84)

1228,2 (462,99)

1241,4 (913,77)

0,642

LDH 24 h (mean (SD)) U/L2/

881,17 (360,74)

963,3 (410,25)

837,29 (324,51)

0,012*

LDH 48 h (mean (SD)) U/L1/

775,05 (342,39)

838,89 (474,2)

742 (245,54)

0,128

IL-6 (mean (SD)) pg/ml2/

63,7 (113,77)

103,93 (161,29)

42,59 (70,28)

0,001*

  1. LDH Lactate dehydrogenase, IL Interleukin, SD Standard deviation; * significant differences between means, based on 1/ T-test y 2/ Mann Whitney U test