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Table 3 Hemogram characteristic in non-survival and survival groups

From: Receiver operating characteristic (ROC) to determine cut-off points of clinical and biomolecular markers to discriminate mortality in severe COVID-19 living at high altitude

Biomarker

Total

Condition at discharge

p-value

No-survival

Survival

Lymphocytes 24 h (mean (SD))2/

673,61 (374,55)

571,23 (412,3)

727,86 (342,26)

0,000*

Lymphocytes 48 h (mean (SD))2/

640,43 (465,85)

564,25 (620,45)

678,51 (361,84)

0,000*

Lymphocytes 72 h (mean (SD))2/

677,34 (524,13)

487,77 (253,12)

769,29 (593,34)

0,000*

Platelets 24 h (mean (SD))2/

337,926,83 (121,822,39)

314,704,23 (121,476,56)

350,231,34 (120,648,8)

0,029*

Platelets 48 h (mean (SD))2/

342,930,35 (126,045,41)

307,298,51 (114,267,9)

360,746,27 (128,265,45)

0,007*

Platelets 72 h (mean (SD))2/

349,395 (124,949,19)

311,727,27 (118,862,11)

367,947,76 (124,113,3)

0,005*

Neutrophils 24 h (mean (SD)) 2/

10,272,45 (5962,01)

11,753,52 (8278,7)

9487,71 (4081,38)

0,024*

Neutrophils 48 h (mean (SD))2/

9400,43 (4205,02)

9872 (3949,17)

9157,51 (4325,43)

0,335

Neutrophils 72 h (mean (SD))2/

11,083,67 (14,321,56)

12,949,55 (21,723,65)

10,143,62 (8403,68)

0,333

Eosinophils 24 h (mean (SD))2/

23,01 (48,88)

20,27 (35,25)

24,46 (54,81)

0,949

Eosinophils 48 h (mean (SD))2/

28,57 (64,17)

23,26 (41,46)

31,3 (73,18)

0,346

Eosinophils 72 h (mean (SD))2/

31,88 (74,32)

29,49 (60,98)

33,08 (80,36)

0,716

NLR 24 h (mean (SD))2/

20,89 (20,46)

28,86 (28,15)

16,67 (13,15)

0,000*

NLR 48 h (mean (SD))2/

20,66 (19,06)

26,41 (22,34)

17,73 (16,49)

0,000*

NLR 72 h (mean (SD))2/

24,25 (39,02)

32,6 (58,6)

20,11 (23,25)

0,000*

  1. SD Standard deviation, NLR Neutrophil-to-lymphocyte ratio; * significant differences of means, based on 1/ T-test y 2/ Mann Whitney U test