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Table 4 Logistic regression to predict OR of mortality based on mechanical ventilation, biomolecular and hemogram markers

From: Receiver operating characteristic (ROC) to determine cut-off points of clinical and biomolecular markers to discriminate mortality in severe COVID-19 living at high altitude

Variables

Univariate

Multivariate

OR

CI-OR 95%

p-value

OR

CI-OR 95%

p-value

Ll

Hl

Ll

Hl

Significant variables

 Ferritin 24 h ≥ 1225 ng/dl

2,46a

1,36

44,46

0,003*

3,31a

1,40

7,79

0,006*

 IL-6 24 h ≥ 11 pg/ml

13,93a

3,23

60,06

 < 0,001*

9,65a

1,94

47,13

0,006*

 PaFiO2 72 h ≤ 164 mmHg

5,09a

2,69

9,62

 < 0,001*

4,12a

1,74

9,76

0,001*

 NLR 24 h ≥ 22

4,90a

2,57

9,36

 < 0,001*

7,29a

3,04

17,49

 < 0,001*

 SOFA 72 h ≥ 6

2,96a

1,58

5,53

0,001*

2,29

0,97

5,41

0,059

  1. IL Interleukin, PaFiO2 ratio of arterial oxygen partial pressure (PaO2 in mmHg) to fractional inspired oxygen, NLR Neutrophil-to-lymphocyte ratio, SOFA Sequential Organ Failure Assessment Score; * significant variables p-value < 0,05, aOR significant odds ratio, CI Confidence interval, Ll Lower limit, Hl Higher limit; based on logistic regression